Membrane Trafficking: A Little Flexibility Helps Vesicles Get into Shape

Formation of a transport vesicle in membrane trafficking pathways requires deformation of the membrane to form a highly curved structure. A recent study reveals a crucial function for the conical lipid lysophosphatidylinositol in reducing the bending rigidity of the membrane during COPII vesicle bud...

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Bibliographic Details
Published in:Current biology 2018-06, Vol.28 (12), p.R706-R709
Main Author: Jackson, Catherine L.
Format: Article
Language:English
Subjects:
Cellular Biology
Life Sciences
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Summary:Formation of a transport vesicle in membrane trafficking pathways requires deformation of the membrane to form a highly curved structure. A recent study reveals a crucial function for the conical lipid lysophosphatidylinositol in reducing the bending rigidity of the membrane during COPII vesicle budding in the early secretory pathway. Formation of a transport vesicle in membrane trafficking pathways requires deformation of the membrane to form a highly curved structure. A recent study reveals a crucial function for the conical lipid lysophosphatidylinositol in reducing the bending rigidity of the membrane during COPII vesicle budding in the early secretory pathway.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2018.04.068