A Metal-Free Route to Heterocyclic Trifluoromethyl- and Fluoroalkylselenolated Molecules

A metal-free methodology to easily synthesize various CF3Se-containing heterocyclic compounds has been developed through intramolecular ring closures of alkynes promoted with CF3SeCl. Moreover, this strategy has also been extended to other fluoroalkylselenyl groups.

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Bibliographic Details
Published in:Organic letters 2018-01, Vol.20 (1), p.56-59
Main Authors: Glenadel, Quentin, Ismalaj, Ermal, Billard, Thierry
Format: Article
Language:English
Subjects:
Chemical Sciences
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Summary:A metal-free methodology to easily synthesize various CF3Se-containing heterocyclic compounds has been developed through intramolecular ring closures of alkynes promoted with CF3SeCl. Moreover, this strategy has also been extended to other fluoroalkylselenyl groups.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.7b03338