Breast magnetic resonance elastography: a review of clinical work and future perspectives

• Published in: NMR in biomedicine 2018-10, Vol.31 (10), p.e3932-n/a
• Main Authors: Bohte, A.E., Nelissen, J.L., Runge, J.H., Holub, O., Lambert, S.A., Graaf, L., Kolkman, S., Meij, S., Stoker, J., Strijkers, G.J., Nederveen, A.J., Sinkus, R.
• Format: Article
• Language: English
• Subjects: Bioengineering; Biological products; Breast; Breast - diagnostic imaging; breast cancer; Data acquisition; Data processing; Elastic Modulus; Elasticity Imaging Techniques; Human health and pathology; Humans; Imaging; Lesions; Life Sciences; Magnetic resonance; magnetic resonance elastography (MRE); Magnetic Resonance Imaging; Metastases; MRI; multi‐frequency; octahedral shear strain; Predictions; Resonance; Tumors; ultrasound elastography
• ISSN: 0952-3480; 1099-1492
• DOI: 10.1002/nbm.3932

This review on magnetic resonance elastography (MRE) of the breast provides an overview of available literature and describes current developments in the field of breast MRE, including new transducer technology for data acquisition and multi‐frequency‐derived power‐law behaviour of tissue. Moreover, we discuss the future potential of breast MRE, which goes beyond its original application as an additional tool in differentiating benign from malignant breast lesions. These areas of ongoing and future research include MRE for pre‐operative tumour delineation, staging, monitoring and predicting response to treatment, as well as prediction of the metastatic potential of primary tumours. This review on magnetic resonance elastography (MRE) of the breast reviews in the available literature, describes current developments, including multi‐frequency‐derived power‐law behaviour of tissue, and discusses the potential of MRE, which includes more than serving as an additional tool in differentiating benign from malignant breast lesions.