Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications

Hybrid lipid oligonucleotide conjugates are finding more and more biotechnological applications. This short critical review highlights their synthesis, supramolecular organization as well as their applications in the field of biotechnology (111 references).

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Bibliographic Details
Published in:Chemical Society reviews 2011-01, Vol.40 (12), p.5844-5854
Main Authors: Patwa, Amit, Gissot, Arnaud, Bestel, Isabelle, Barthélémy, Philippe
Format: Article
Language:English
Subjects:
Animals
Biochemistry, Molecular Biology
Biomedical Research - methods
Biophysics
Cell Membrane - metabolism
Chemical Sciences
Chemistry Techniques, Synthetic - methods
Drug Design
Hybrids
Life Sciences
Lipid Metabolism
Oligonucleotides - chemical synthesis
Oligonucleotides - chemistry
Oligonucleotides - metabolism
Organic chemistry
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Description
Summary:Hybrid lipid oligonucleotide conjugates are finding more and more biotechnological applications. This short critical review highlights their synthesis, supramolecular organization as well as their applications in the field of biotechnology (111 references).
ISSN:0306-0012
1460-4744
DOI:10.1039/c1cs15038c