Numerical modelling challenges for clinical electroporation ablation technique of liver tumors

Electroporation ablation is a promising non surgical and minimally invasive technique of tumor ablation, for which no monitoring is currently available. In this paper, we present the recent advances and challenges on the numerical modeling of clinical electroporation ablation of liver tumors. In par...

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Bibliographic Details
Published in:Mathematical modelling of natural phenomena 2020, Vol.15, p.11
Main Authors: Gallinato, Olivier, de Senneville, Baudouin Denis, Seror, Olivier, Poignard, Clair
Format: Article
Language:English
Subjects:
Ablation
Analysis of PDEs
Computer applications
Electric fields
Electroporation
Liver
Mathematical models
Mathematics
Tumors
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Summary:Electroporation ablation is a promising non surgical and minimally invasive technique of tumor ablation, for which no monitoring is currently available. In this paper, we present the recent advances and challenges on the numerical modeling of clinical electroporation ablation of liver tumors. In particular, we show that a nonlinear static electrical model of tissue combined with clinical imaging can give crucial information of the electric field distribution in the clinical configuration. We conclude the paper by presenting some important questions that have to be addressed for an effective impact of computational modeling in clinical practice of electroporation ablation.
ISSN:0973-5348
1760-6101
DOI:10.1051/mmnp/2019037