Circulating vitamin D concentration and age-related macular degeneration: Systematic review and meta-analysis

Highlights • Vitamin D may be involved in ocular health and function. • High concentrations 25-hydroxyvitamin D are associated with less age-related macular degeneration. • Concentrations of 25-hydroxyvitamin D under 50nmol/L are associated with late-stage age-related macular degeneration. • These f...

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Bibliographic Details
Published in:Maturitas 2016-06, Vol.88, p.101-112
Main Authors: Annweiler, Cedric, Drouet, Morgane, Duval, Guillaume T, Paré, Pierre-Yves, Lerue, Stephanie, Dinomais, Mickael, Milea, Dan
Format: Article
Language:English
Subjects:
Age-related macular degeneration
Cross-Sectional Studies
Eye
Humans
Internal Medicine
Life Sciences
Macular Degeneration - blood
Macular Degeneration - complications
Meta-analysis
Neuroendocrinology
Obstetrics and Gynecology
Older adults
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - complications
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Summary:Highlights • Vitamin D may be involved in ocular health and function. • High concentrations 25-hydroxyvitamin D are associated with less age-related macular degeneration. • Concentrations of 25-hydroxyvitamin D under 50nmol/L are associated with late-stage age-related macular degeneration. • These findings provide a scientific basis for vitamin D replacement trials.
ISSN:0378-5122
1873-4111
DOI:10.1016/j.maturitas.2016.04.002