Prevalence and Macrolide Resistance of Mycoplasma genitalium in South African Women

Remnant specimens from 601 women obtained in a cross-sectional study from rural South Africa were tested for Mycoplasma genitalium. Overall, 10.8% of women were infected with M. genitalium either in the vagina or in the rectum. Macrolide resistance, although of low prevalence, in M. genitalium is de...

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Bibliographic Details
Published in:Sexually transmitted diseases 2015-03, Vol.42 (3), p.140-142
Main Authors: Hay, Bastien, Dubbink, Jan Henk, Ouburg, Sander, Le Roy, Chloé, Pereyre, Sabine, van der Eem, Lisette, Morré, Servaas A., Bébéar, Cécile, Peters, Remco P.H.
Format: Article
Language:English
Subjects:
Adult
Anti-Bacterial Agents - pharmacology
Antibiotics
Bacteria
Bacterial infections
Cervix Uteri - microbiology
Cross-Sectional Studies
DNA, Bacterial - drug effects
Drug resistance
Drug Resistance, Bacterial - genetics
Female
Humans
Life Sciences
Middle Aged
Mycoplasma genitalium - genetics
Mycoplasma genitalium - isolation & purification
Mycoplasma Infections - epidemiology
Mycoplasma Infections - genetics
Mycoplasma Infections - microbiology
Point Mutation
Prevalence
Real-Time Polymerase Chain Reaction
Rectum - microbiology
Risk Factors
RNA, Ribosomal, 23S - genetics
Rural areas
Sequence Analysis, DNA
South Africa - epidemiology
Vagina - microbiology
Womens health
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Description
Summary:Remnant specimens from 601 women obtained in a cross-sectional study from rural South Africa were tested for Mycoplasma genitalium. Overall, 10.8% of women were infected with M. genitalium either in the vagina or in the rectum. Macrolide resistance, although of low prevalence, in M. genitalium is described for the first time in Sub-Saharan Africa.
ISSN:0148-5717
1537-4521
DOI:10.1097/OLQ.0000000000000246