In vitro effects of Musa x paradisiaca extracts on four developmental stages of Haemonchus contortus

This study was carried out to evaluate the in vitro effect of Musa x paradisiaca stem and leaf against the parasitic nematode of small ruminants Haemonchus contortus. Three extracts (aqueous, methanolic and/or dichloromethane) of Musa x paradisiaca stem and leaf were tested in vitro on four developm...

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Bibliographic Details
Published in:Research in veterinary science 2014-02, Vol.96 (1), p.127-132
Main Authors: Marie-Magdeleine, C., Udino, L., Philibert, L., Bocage, B., Archimede, H.
Format: Article
Language:English
Subjects:
Adult worm motility
Animals
Anthelmintics - pharmacology
Banana tree
Chemical and Process Engineering
Chromatography, Thin Layer
Dose-Response Relationship, Drug
Egg hatching
Engineering Sciences
Food engineering
Gastro-intestinal nematodes
Guadeloupe
Haemonchus - growth & development
In vitro assay
In Vitro Techniques
L3 migration
Larva - growth & development
Larval development
Leaves
Life Sciences
Metabolites
Motility
Musa - chemistry
Phytotherapy - methods
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plant Stems - chemistry
Regression Analysis
Veterinary medicine
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Summary:This study was carried out to evaluate the in vitro effect of Musa x paradisiaca stem and leaf against the parasitic nematode of small ruminants Haemonchus contortus. Three extracts (aqueous, methanolic and/or dichloromethane) of Musa x paradisiaca stem and leaf were tested in vitro on four developmental stages of H. contortus using egg hatch assay (EHA), larval development assay (LDA), L3 migration inhibition assay (LMI) and adult worm motility assay (AWM). The highly significant (P67% for each extract) and the negative effect of the dichloromethane extract of leaf on adult worm motility (43% of inhibition of motility after 24h of incubation) compared to the negative controls, suggest anthelmintic properties of Musa x paradisiaca stem and leaf against H. contortus. The active principles responsible for the activity could be secondary metabolites such as terpenoid and flavonoid compounds present in the leaf and stem of the plant.
ISSN:0034-5288
1532-2661
DOI:10.1016/j.rvsc.2013.12.004