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Identification of atypical scrapie in Canadian sheep
Scrapie, a transmissible spongiform encephalopathy of sheep and goats, exists in most small ruminant-producing countries of the world. A novel form of this disease was recently recognized and is known by various names, including Nor98, Nor98-like, and atypical scrapie. Differing from classic scrapie...
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| Published in: | Journal of veterinary diagnostic investigation 2010-05, Vol.22 (3), p.408-411 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c510t-95142fa9ed4c5da1ea92dc30b8ca2ddda08eb32b1bf68478261179598693fcf93 |
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| cites | cdi_FETCH-LOGICAL-c510t-95142fa9ed4c5da1ea92dc30b8ca2ddda08eb32b1bf68478261179598693fcf93 |
| container_end_page | 411 |
| container_issue | 3 |
| container_start_page | 408 |
| container_title | Journal of veterinary diagnostic investigation |
| container_volume | 22 |
| creator | Mitchell, Gordon B O'Rourke, Katherine I Harrington, Noel P Soutyrine, Andrei Simmons, Marion M Dudas, Sandor Zhuang, Dongyue Laude, Hubert Balachandran, Aru |
| description | Scrapie, a transmissible spongiform encephalopathy of sheep and goats, exists in most small ruminant-producing countries of the world. A novel form of this disease was recently recognized and is known by various names, including Nor98, Nor98-like, and atypical scrapie. Differing from classic scrapie in epidemiology, histopathology, and biochemical characteristics, atypical scrapie cases have been identified throughout Europe and in the United States. Enhanced scrapie surveillance efforts recently identified 3 cases of atypical scrapie in Canada. |
| doi_str_mv | 10.1177/104063871002200310 |
| format | article |
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A novel form of this disease was recently recognized and is known by various names, including Nor98, Nor98-like, and atypical scrapie. Differing from classic scrapie in epidemiology, histopathology, and biochemical characteristics, atypical scrapie cases have been identified throughout Europe and in the United States. Enhanced scrapie surveillance efforts recently identified 3 cases of atypical scrapie in Canada.</description><identifier>ISSN: 1040-6387</identifier><identifier>EISSN: 1943-4936</identifier><identifier>DOI: 10.1177/104063871002200310</identifier><identifier>PMID: 20453215</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Animals ; atypical scrapie ; Blotting, Western ; Canada - epidemiology ; Codon - genetics ; diagnostic techniques ; disease detection ; disease prevalence ; disease surveillance ; emerging diseases ; epidemiological studies ; geographical distribution ; Goat Diseases - epidemiology ; Goat Diseases - virology ; Goats ; Immunoblotting - methods ; Life Sciences ; Nor98 scrapie ; Nor98-like scrapie ; pathotypes ; Prion Diseases - diagnosis ; Prion Diseases - epidemiology ; Prion Diseases - veterinary ; Prion Diseases - virology ; Prions - genetics ; Prions - pathogenicity ; PrPSc Proteins - classification ; PrPSc Proteins - genetics ; PrPSc Proteins - pathogenicity ; risk assessment ; scrapie ; Scrapie - epidemiology ; Sheep ; Sheep Diseases - epidemiology ; Sheep Diseases - virology ; strains ; United States</subject><ispartof>Journal of veterinary diagnostic investigation, 2010-05, Vol.22 (3), p.408-411</ispartof><rights>2010 American Association of Veterinary Laboratory Diagnosticians</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-95142fa9ed4c5da1ea92dc30b8ca2ddda08eb32b1bf68478261179598693fcf93</citedby><cites>FETCH-LOGICAL-c510t-95142fa9ed4c5da1ea92dc30b8ca2ddda08eb32b1bf68478261179598693fcf93</cites><orcidid>0000-0002-0732-445X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20453215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.inrae.fr/hal-02655583$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Mitchell, Gordon B</creatorcontrib><creatorcontrib>O'Rourke, Katherine I</creatorcontrib><creatorcontrib>Harrington, Noel P</creatorcontrib><creatorcontrib>Soutyrine, Andrei</creatorcontrib><creatorcontrib>Simmons, Marion M</creatorcontrib><creatorcontrib>Dudas, Sandor</creatorcontrib><creatorcontrib>Zhuang, Dongyue</creatorcontrib><creatorcontrib>Laude, Hubert</creatorcontrib><creatorcontrib>Balachandran, Aru</creatorcontrib><title>Identification of atypical scrapie in Canadian sheep</title><title>Journal of veterinary diagnostic investigation</title><addtitle>J Vet Diagn Invest</addtitle><description>Scrapie, a transmissible spongiform encephalopathy of sheep and goats, exists in most small ruminant-producing countries of the world. 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Enhanced scrapie surveillance efforts recently identified 3 cases of atypical scrapie in Canada.</description><subject>Animals</subject><subject>atypical scrapie</subject><subject>Blotting, Western</subject><subject>Canada - epidemiology</subject><subject>Codon - genetics</subject><subject>diagnostic techniques</subject><subject>disease detection</subject><subject>disease prevalence</subject><subject>disease surveillance</subject><subject>emerging diseases</subject><subject>epidemiological studies</subject><subject>geographical distribution</subject><subject>Goat Diseases - epidemiology</subject><subject>Goat Diseases - virology</subject><subject>Goats</subject><subject>Immunoblotting - methods</subject><subject>Life Sciences</subject><subject>Nor98 scrapie</subject><subject>Nor98-like scrapie</subject><subject>pathotypes</subject><subject>Prion Diseases - diagnosis</subject><subject>Prion Diseases - epidemiology</subject><subject>Prion Diseases - veterinary</subject><subject>Prion Diseases - virology</subject><subject>Prions - genetics</subject><subject>Prions - pathogenicity</subject><subject>PrPSc Proteins - classification</subject><subject>PrPSc Proteins - genetics</subject><subject>PrPSc Proteins - pathogenicity</subject><subject>risk assessment</subject><subject>scrapie</subject><subject>Scrapie - epidemiology</subject><subject>Sheep</subject><subject>Sheep Diseases - epidemiology</subject><subject>Sheep Diseases - virology</subject><subject>strains</subject><subject>United States</subject><issn>1040-6387</issn><issn>1943-4936</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp9kEtr3TAQRkVoaB7tH8ii9a5k4WRGD1tahkvbBC500WYtxnokCr62a_kG8u-ri9NsCl2NRpzvwHyMXSBcIbbtNYKERugWATgHEAhH7BSNFLU0onlX3gWoD8QJO8v5CUBx1eJ7dsJBKsFRnTJ558OwpJgcLWkcqjFWtLxMZe2r7GaaUqjSUG1oIJ9oqPJjCNMHdhypz-Hj6zxn99--_trc1tsf3-82N9vaKYSlNgolj2SCl055wkCGeyeg0464955Ah07wDrvYaNlq3pSzjDK6MSK6aMQ5u1y9j9TbaU47ml_sSMne3mzt4Q94o5TS4hkL-2Vlp3n8vQ95sbuUXeh7GsK4z7YVgnNtJBSSr6Sbx5znEN_UCPZQrP232BL69Krfd7vg3yJ_myzA9Qpkegj2adzPQ6nm_8rPayLSaOlhTtne_-SAAlArjsaIP80UhwI</recordid><startdate>20100501</startdate><enddate>20100501</enddate><creator>Mitchell, Gordon B</creator><creator>O'Rourke, Katherine I</creator><creator>Harrington, Noel P</creator><creator>Soutyrine, Andrei</creator><creator>Simmons, Marion M</creator><creator>Dudas, Sandor</creator><creator>Zhuang, Dongyue</creator><creator>Laude, Hubert</creator><creator>Balachandran, Aru</creator><general>SAGE Publications</general><general>American Association of Veterinary Laboratory Diagnosticians</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0002-0732-445X</orcidid></search><sort><creationdate>20100501</creationdate><title>Identification of atypical scrapie in Canadian sheep</title><author>Mitchell, Gordon B ; 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| identifier | ISSN: 1040-6387 |
| ispartof | Journal of veterinary diagnostic investigation, 2010-05, Vol.22 (3), p.408-411 |
| issn | 1040-6387 1943-4936 |
| language | eng |
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| source | Sage Journals Online |
| subjects | Animals atypical scrapie Blotting, Western Canada - epidemiology Codon - genetics diagnostic techniques disease detection disease prevalence disease surveillance emerging diseases epidemiological studies geographical distribution Goat Diseases - epidemiology Goat Diseases - virology Goats Immunoblotting - methods Life Sciences Nor98 scrapie Nor98-like scrapie pathotypes Prion Diseases - diagnosis Prion Diseases - epidemiology Prion Diseases - veterinary Prion Diseases - virology Prions - genetics Prions - pathogenicity PrPSc Proteins - classification PrPSc Proteins - genetics PrPSc Proteins - pathogenicity risk assessment scrapie Scrapie - epidemiology Sheep Sheep Diseases - epidemiology Sheep Diseases - virology strains United States |
| title | Identification of atypical scrapie in Canadian sheep |
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