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Embryonic Stem Cells in Cattle

Contents Because of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be iso...

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Published in:Reproduction in domestic animals 2008-10, Vol.43 (s4), p.32-37
Main Authors: Muñoz, M, Díez, C, Caamaño, JN, Jouneau, A, Hue, I, Gómez, E
Format: Article
Language:English
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Summary:Contents Because of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated. In this paper, we will summarize the current knowledge on bovine ESCs in an attempt to understand why derivation of domestic animal ESC is still unsuccessful and we will discuss some promising future approaches.
ISSN:0936-6768
1439-0531
DOI:10.1111/j.1439-0531.2008.01229.x