quantiNemo: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation

• Published in: Bioinformatics 2008-07, Vol.24 (13), p.1552-1553
• Main Authors: Neuenschwander, Samuel, Hospital, Frédéric, Guillaume, Frédéric, Goudet, Jérôme
• Format: Article
• Language: English
• Subjects: Algorithms; Animals; Biological and medical sciences; Chromosome Mapping - methods; Computer Simulation; Fundamental and applied biological sciences. Psychology; General aspects; Genetics, Population; Humans; Life Sciences; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Models, Genetic; Quantitative Trait Loci - genetics; Quantitative Trait, Heritable; Software
• ISSN: 1367-4803; 1460-2059; 1367-4811
• DOI: 10.1093/bioinformatics/btn219

quantiNemo is an individual-based, genetically explicit stochastic simulation program. It was developed to investigate the effects of selection, mutation, recombination and drift on quantitative traits with varying architectures in structured populations connected by migration and located in a heterogeneous habitat. quantiNemo is highly flexible at various levels: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography, mating system, etc. quantiNemo is coded in C++ using an object-oriented approach and runs on any computer platform. Availability: Executables for several platforms, user's manual, and source code are freely available under the GNU General Public License at http://www2.unil.ch/popgen/softwares/quantinemo Contact: [e-mail]