Effects of Rapeseed Meal-Glucosinolates on Thyroid Metabolism and Feed Utilization in Rainbow Trout

Two rapeseed meals (RM1 and RM2), containing glucosinolates at a concentration of 26 and 40 μmol/g, respectively, were incorporated at increasing levels (10, 20, and 30% for RM1 and 30 and 50% for RM2) in diets of juvenile rainbow trout. Disturbances in the thyroid axis appeared after 14 days of fee...

Full description

Saved in:
Bibliographic Details
Published in:General and comparative endocrinology 2001-12, Vol.124 (3), p.343-358
Main Authors: Burel, C., Boujard, T., Kaushik, S.J., Boeuf, G., Mol, K.A., Van der Geyten, S., Darras, V.M., Kühn, E.R., Pradet-Balade, B., Quérat, B., Quinsac, A., Krouti, M., Ribaillier, D.
Format: Article
Language:English
Subjects:
Animal Nutritional Physiological Phenomena
Animals
Brassica rapa - chemistry
deiodinase activity
Diet
Endocrinology and metabolism
glucosinolates
Glucosinolates - administration & dosage
Glucosinolates - pharmacology
growth
Human health and pathology
Iodide Peroxidase - metabolism
iodine
Iodine - administration & dosage
Life Sciences
Oncorhynchus mykiss
Oncorhynchus mykiss - growth & development
Oncorhynchus mykiss - physiology
rainbow trout
rapeseed
Seawater
thyroid function
Thyroid Gland - drug effects
Thyroid Gland - metabolism
Thyrotropin - pharmacology
Thyroxine - blood
Triiodothyronine - administration & dosage
Triiodothyronine - blood
TSH
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two rapeseed meals (RM1 and RM2), containing glucosinolates at a concentration of 26 and 40 μmol/g, respectively, were incorporated at increasing levels (10, 20, and 30% for RM1 and 30 and 50% for RM2) in diets of juvenile rainbow trout. Disturbances in the thyroid axis appeared after 14 days of feeding (with a dietary incorporation level of 10%). The dietary supplementation with T3 or iodine induced an increase in plasma T3 levels, compared to that in fish fed the RM diets, and reduced the deleterious effect of RM on growth. When trout were reared in seawater, there was also a slight increase in thyroid hormone levels. TSH treatment had no effect on the thyroid hormone plasma levels. The incorporation of 30% of RM1, which induced a lower dietary content of toxic compounds than RM2, led to a rapid decrease of plasma T4 and T3 levels, but growth was affected only after 6 months of feeding. During these studies, the deiodinase activities responded in a complex manner to restore plasma and tissue levels of T3.
ISSN:0016-6480
1095-6840
DOI:10.1006/gcen.2001.7723