Modes of phagocytosis of Gram-positive and Gram-negative bacteria by Spodoptera littoralis granular haemocytes

Haemocytes are the main immunocompetent cells in insect cellular immune reactions. Here, we show that in Spodoptera littoralis, granular haemocytes are the primary phagocyte haemocytes, both in vivo and in vitro. The “trigger” and “zipper” modes of engulfment known in mammal macrophages are active,...

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Bibliographic Details
Published in:Journal of insect physiology 2005, Vol.51 (1), p.39-46
Main Authors: Costa, Sónia C.P., Ribeiro, Carlos, Girard, Pierre-Alain, Zumbihl, Robert, Brehélin, Michel
Format: Article
Language:English
Subjects:
Animals
binding properties
Cell Membrane - physiology
cell-mediated immunity
Corynebacterium - immunology
Corynebacterium xerosis
Escherichia coli
Escherichia coli - immunology
Gram-negative bacteria
Gram-positive bacteria
granular hemocytes
hemocytes
Hemocytes - immunology
inhibitors
Insect
insect immunity
Life Sciences
lipopolysaccharides
lipoteichoic acid
Macropinocytosis
Noctuidae
Phagocytes - immunology
phagocytosis
Phagocytosis - physiology
Receptor
receptors
scavenger receptors
Spodoptera - cytology
Spodoptera - immunology
Spodoptera littoralis
Trigger
Zipper
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Summary:Haemocytes are the main immunocompetent cells in insect cellular immune reactions. Here, we show that in Spodoptera littoralis, granular haemocytes are the primary phagocyte haemocytes, both in vivo and in vitro. The “trigger” and “zipper” modes of engulfment known in mammal macrophages are active, in vivo, in S. littoralis granular haemocytes, together with macropinocytosis. Lipopolysaccharide as well as lipoteichoic acid inhibit the binding of both Gram-positive ( Corynebacterium xerosis) and Gram-negative ( Escherichia coli) bacteria on granular haemocytes. In addition, different ligands can inhibit the binding of E. coli. Most of these inhibitors are known as ligands of scavenger receptors in mammal macrophages and we hypothesise that one of the receptors present on S. littoralis granular haemocytes could be a scavenger-like receptor.
ISSN:0022-1910
1879-1611
DOI:10.1016/j.jinsphys.2004.10.014