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Long-Term Mortality of Stroke Survivors in Parakou: 5-Year Follow-Up
Background: The burden of stroke is high in Africa, but few data are available on the long-term outcome of strokes in this area. Aim: We aimed to study the long-term outcome of stroke survivors in Parakou from 2012 to 2018. Methods of Study: It was a cohort study and included 247 stroke patients adm...
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Published in: | Journal of stroke and cerebrovascular diseases 2020-06, Vol.29 (6), p.104785-104785, Article 104785 |
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Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
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Online Access: | Get full text |
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Summary: | Background: The burden of stroke is high in Africa, but few data are available on the long-term outcome of strokes in this area. Aim: We aimed to study the long-term outcome of stroke survivors in Parakou from 2012 to 2018. Methods of Study: It was a cohort study and included 247 stroke patients admitted to the University Hospital of Parakou from January 1, 2012 to April 30, 2018. Each patient was followed up for at least 1 year. The modified RANKIN scale was used to evaluate patients. Verbal autopsy was used to ascertain the cause of death. The survival probability was estimated using the Kaplan-Meier method. Predictors of mortality were estimated using the Cox proportional model and the hazard ratio (HR) and their 95% confidence intervals were determined. The data were analyzed using Stata Software. Results: The mean age was 58.1 ± 13.4 years with a sex ratio of 1.12. Among stroke survivors, the mortality was 10.1% at 3 months, 11.7% at 6 months, 15.4% at 1 year, 21.5% at 3 years, and 23.5% at 5 years. The probability of survival after a stroke was 66.5% at 5 years. Factors associated with mortality were age with adjusted HR 1.4 (1.2-1.7) for each 10 years, male sex with aHR 2.3 (1.2-4.6), history of hypertension with aHR 2.0 (1.0-4.1) and the severity of the initial neurological impairment National Institute of Health Stroke Scale with aHR 1.1 (1.0-1.2) for each 1 point. The main causes of death were recurrent stroke, infectious diseases, and cardiac disease. The proportion of patients with functional disability was 53.8% at 1 year. The quality of life was generally impaired in terms of physical health, personal environment, and finances. Conclusions: The long-term prognosis of stroke patients in Parakou is poor. It requires urgent action to reduce this burden. |
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ISSN: | 1052-3057 1532-8511 |
DOI: | 10.1016/j.jstrokecerebrovasdis.2020.104785 |