Embryons vitrifiés, embryons frais : comparaison des poids de naissance

• Published in: Gynécologie, obstétrique, fertilité & sénologie obstétrique, fertilité & sénologie, 2019-03, Vol.47 (3), p.305-310
• Main Authors: Maris, E., Ferrieres-Hoa, A., Gala, A., Coffy, A., Vintejoux, E., Ranisavljevic, N., Hamamah, S.
• Format: Article
• Language: fre
• Subjects: Gynecology and obstetrics; Human health and pathology; Life Sciences
• ISSN: 2468-7189; 2468-7197; 2468-7189
• DOI: 10.1016/j.gofs.2019.01.011

It is already known that children born after slow frozen embryo replacement have a significantly higher birth weight compared to children born after fresh embryo transfer. Similar data have been reported related to frozen embryo transfer using an open vitrification system. However, few data relative to birth weight using a complete embryo closed vitrification system has been reported. The purpose of this study was to know if frozen embryo in closed vitrification system is associated with a higher birth weight compared to fresh embryo replacement.Design: This was a monocentric retrospective cohort study, 371 children were issued from fresh embryo replacement and 127 from vitrified embryo transfer.Materials and methods: All singletons born after fresh or vitrified embryo transfer between January 2011 and April 2015 were included. Births from the vitrified or fresh transfers of egg or sperm donation, and preimplantation genetic diagnosis were excluded. In addition, pregnancies with more than one gestational sac at the first ultrasound were excluded. An analysis of covariance (ANCOVA) was used for multivariate analysis.Results: Mean birth weight was 205g higher in the frozen embryo compared with fresh embryos transfer groups (3368g vs. 3163g respectively, P