Fourth branchial anomalies: Predictive factors of therapeutic success

• Published in: Journal of pediatric surgery 2019-08, Vol.54 (8), p.1702-1707
• Main Authors: Rossi, Marie-Eva, Moreddu, Eric, Leboulanger, Nicolas, Akkari, Mohamed, Triglia, Jean-Michel, Mondain, Michel, Nicollas, Richard, Denoyelle, Françoise
• Format: Article
• Language: English
• Subjects: Abscess - etiology; Adolescent; Branchial Region - abnormalities; Branchial Region - surgery; Child; Child, Preschool; Congenital malformations; Dyspnea - etiology; Endoscopic cauterization; Endoscopy; Female; Fourth branchial pouch; Humans; Infant; Infant, Newborn; Life Sciences; Male; Neck - surgery; Open-neck surgery; Recurrence; Recurrent neck abscess; Retrospective Studies; Risk Factors; Treatment Outcome
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/j.jpedsurg.2019.02.005

The purpose of this work was to determine the epidemiology and the predictive factors of success of the surgical management of fourth branchial anomalies. This is a multicentric retrospective review from 1998 to 2016 of patients who presented with an endoscopically-confirmed fourth branchial pouch anomaly. Data were analyzed according to sex, age, clinical features, number of recurrences, treatment modalities (endoscopic and/or cervicotomy), post-operative complications and follow-up. Fifty-two children have been included. The average age at diagnosis was 4.5 years. Among them, 73.1% were female, 11.4% were neonatal forms; 94.2% of lesions were left-sided; 75% of patients presented a cervical abscess as first symptom, and 7.7% of children presented with dyspnea. Average time between first symptoms and management was 9.5 months. Management was endoscopic in 73.1% of patients (laser in 84.2%, coagulation in 15.8%) with about a third of recurrence after one procedure. Overall success of endoscopic procedures reached 84.2%. A cervical open surgery was performed in 26.9% as first line treatment. Overall success of cervicotomy reached 85.7%. No complications of endoscopic surgery have been identified. There were 35.7% complications of cervicotomy (2 recurrent nerve palsy, 2 keloid scars, 1 pharyngostoma). An association was proved between recurrences and initial abscess (OR = 2.44), and with age between 3 and 5 (OR = 4). Endoscopic treatments appear to be effective in first line approach in the management of fourth branchial anomalies, offering an excellent efficiency with rare complications. We identified two risk factors of recurrence: age between 3 and 5 years old and history of cervical abscesses. IV.