Multimodality Imaging Features of a Misleading Sacral Giant Cell Tumor in 18F-FDG PET/CT, Bone Scan, and MRI

ABSTRACTWe report the case of an asymptomatic 66-year-old woman referred for initial staging of an invasive ductal breast carcinoma. Initial workup incidentally revealed a bone tumor of right sacral wing corresponding to a giant cell tumor (GCT). We present the imaging characteristics of GCT on Tc-H...

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Bibliographic Details
Published in:Clinical nuclear medicine 2020-10, Vol.45 (10), p.800-801
Main Authors: Dejust, Sebastien, Jallerat, Pascaline, Soibinet-Oudot, Pauline, Jouannaud, Christelle, Morland, David
Format: Article
Language:English
Subjects:
Aged
Bioengineering
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - pathology
Female
Fluorodeoxyglucose F18
Giant Cell Tumors - diagnostic imaging
Giant Cell Tumors - pathology
Humans
Life Sciences
Magnetic Resonance Imaging
Nuclear medicine
Positron Emission Tomography Computed Tomography
Sacrum - diagnostic imaging
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Summary:ABSTRACTWe report the case of an asymptomatic 66-year-old woman referred for initial staging of an invasive ductal breast carcinoma. Initial workup incidentally revealed a bone tumor of right sacral wing corresponding to a giant cell tumor (GCT). We present the imaging characteristics of GCT on Tc-HDP bone scan (doughnut sign), F-FDG PET/CT (intense and heterogeneous uptake of a prominent geographic lytic lesion with partial rupture of cortical), and MRI (hyposignal with gadolinium enhancement on T1-weighted images and heterogeneous hypersignal on T2-weighted images). GCT is a benign but locally aggressive primary bone tumor, constituting a pitfall and diagnostic challenge.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000003148