Hepatic Metastases From Prostatic Adenocarcinoma Without Elevated 18F-Choline Activity

ABSTRACTWe report the case of a 69-year-old man referred for F-fluorocholine (FCH) PET/CT for a biochemical recurrence of prostate cancer. FCH PET/CT demonstrated 2 hypodense hepatic lesions with no uptake but progressing in size compared with a previous assessment. MRI showed a suspicious periphera...

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Bibliographic Details
Published in:Clinical nuclear medicine 2018-10, Vol.43 (10), p.780-781
Main Authors: Dejust, Sébastien, Messaoud, Leila, Jallerat, Pascaline, Marical, Victoria, Morland, David
Format: Article
Language:English
Subjects:
Bioengineering
Life Sciences
Nuclear medicine
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Summary:ABSTRACTWe report the case of a 69-year-old man referred for F-fluorocholine (FCH) PET/CT for a biochemical recurrence of prostate cancer. FCH PET/CT demonstrated 2 hypodense hepatic lesions with no uptake but progressing in size compared with a previous assessment. MRI showed a suspicious peripheral contrast enhancement, raising the question of a liver metastasis. Histopathologic examination concluded to a prostate adenocarcinoma metastasis. This case highlights an unusual pitfall in FCH PET/CTthe lack of uptake in prostatic liver metastasis is presumably due to the partial volume effect induced by the necrotic center and the high uptake of the liver.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000002254