Partial pharyngolaryngectomy with infrahyoid flap: Our experience

We evaluated a cohort of advanced hypopharyngeal squamous cell carcinoma, treated with conservative surgery, reconstruction with infrahyoid flap and radio-chemotherapy. We used partial pharyngo-laryngectomy and radio-chemotherapy to treat fifty-seven patients with stage III–IV hypopharyngeal SCC fro...

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Bibliographic Details
Published in:American journal of otolaryngology 2019-11, Vol.40 (6), p.102271-102271, Article 102271
Main Authors: Cortese, Sophie, Muratori, Enrico, Mastronicola, Romina, Roch, Medarine, Beulque, Emilie, Rauch, P., Dekerle, Lucie, Deganello, Alberto, Dolivet, Gilles
Format: Article
Language:English
Subjects:
Aged
Cancer therapies
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Chemotherapy
Cohort Studies
Disease
Dissection
Evaluation
Female
Human health and pathology
Humans
Hypopharyngeal Neoplasms - mortality
Hypopharyngeal Neoplasms - pathology
Hypopharyngeal Neoplasms - surgery
Hypopharyngeal squamous cell carcinoma
Hypopharynx
Infrahyoid flap
Laryngectomy
Life Sciences
Male
Medical prognosis
Middle Aged
Neoplasm Staging
Ostomy
Patients
Pharyngectomy
Preservation
Radiation therapy
Reconstructive Surgical Procedures
Remission
Sinuses
Squamous cell carcinoma
Surgery
Surgical Flaps
Survival Rate
Throat cancer
Thyroid gland
Tumors
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Summary:We evaluated a cohort of advanced hypopharyngeal squamous cell carcinoma, treated with conservative surgery, reconstruction with infrahyoid flap and radio-chemotherapy. We used partial pharyngo-laryngectomy and radio-chemotherapy to treat fifty-seven patients with stage III–IV hypopharyngeal SCC from November 1994 to December 2011. Clinical examination and speech therapy evaluation were used for estimation of laryngeal function. All patients received a partial pharyngo-laryngectomy. All patients underwent neck dissection; 56 patients received bilateral neck dissection. Reconstruction was achieved by infra-hyoid flap. Five-year overall and disease-specific survival rates were 54.4% and 61.4%, respectively. Successful laryngeal function preservation with complete five-year remission was achieved in 44% of the patients. Selected even if advanced carcinomas of the hypopharynx maybe treated with partial pharyngo-laryngectomy with reconstruction with pedicled flap. Both oncological and functional results showed a good outcome.
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2019.08.002