Quality controls on cord blood unit contiguous segments: Recommendation of the SFGM-TC

• Published in: Pathologie biologie (Paris) 2014-08, Vol.62 (4), p.218-220
• Main Authors: De Vos, J., Birebent, B., Faucher, C., Giet, O., Hicheri, Y., Lemarie, C., Baudoux, E., Boulanger, F., Garnier, F., Larghero, J., Pouthier, F., Thibert, J.-B., Yakoub-Agha, I.
• Format: Article
• Language: English
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Attached segment; Biological and medical sciences; Blood Preservation - methods; Blood Preservation - standards; Bone marrow, stem cells transplantation. Graft versus host reaction; BU release; Cord Blood Stem Cell Transplantation - standards; Cord blood transplantation; Cryopreservation - methods; Cryopreservation - standards; Fetal Blood; France; Greffe de sang de cordon; Histocompatibility Testing; Humans; Life Sciences; Medical sciences; Quality Control; Segment attaché; Specifications; Spécifications; Stem Cells; Transfusions. Complications. Transfusion reactions. Cell and gene therapy
• ISSN: 0369-8114; 1768-3114
• DOI: 10.1016/j.patbio.2014.05.005

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapies (SFGM-TC) set up its fourth annual series of workshops which brought together practitioners from all of its member centers. These workshops took place in September 2013 in Lille. Literature and intra-laboratories studies suggest that attached segment is representative of cord blood unit (CBU). Nevertheless, some discrepancies have been observed when analyzing large data registries. To address these issues, we have listed recommendations to increase the standardization of segment processing and quality control (QC), information on units of measurement and specifications and action to be taken in case of out of specifications QC results on segment. Dans une démarche qui vise à uniformiser les procédures d’allogreffe de cellules souches hématopoïétiques (CSH), la Société française de greffe de moelle et de thérapie cellulaire (SFGM-TC) a organisé les quatrièmes ateliers d’harmonisation des pratiques en septembre 2013 à Lille. Cet atelier a été consacré au segment attaché des unités de sang placentaire dans le but d’établir des recommandations quant à la standardisation du traitement de ce segment et les mesures à prendre en cas de rupture de ce segment.