ST-Segment Elevation Myocardial Infarction Following Transcatheter Aortic Valve Replacement

• Published in: Journal of the American College of Cardiology 2021-05, Vol.77 (17), p.2187-2199
• Main Authors: Faroux, Laurent, Lhermusier, Thibault, Vincent, Flavien, Nombela-Franco, Luis, Tchétché, Didier, Barbanti, Marco, Abdel-Wahab, Mohamed, Windecker, Stephan, Auffret, Vincent, Campanha-Borges, Diego Carter, Fischer, Quentin, Muñoz-Garcia, Erika, Trillo-Nouche, Ramiro, Jorgensen, Troels, Serra, Vicens, Toggweiler, Stefan, Tarantini, Giuseppe, Saia, Francesco, Durand, Eric, Donaint, Pierre, Gutierrez-Ibanes, Enrique, Wijeysundera, Harindra C, Veiga, Gabriela, Patti, Giuseppe, D'Ascenzo, Fabrizio, Moreno, Raul, Hengstenberg, Christian, Chamandi, Chekrallah, Asmarats, Lluis, Hernandez-Antolin, Rosana, Gomez-Hospital, Joan Antoni, Cordoba-Soriano, Juan Gabriel, Landes, Uri, Jimenez-Diaz, Victor Alfonso, Cruz-Gonzalez, Ignacio, Nejjari, Mohammed, Roubille, François, Van Belle, Éric, Armijo, German, Siddiqui, Saifullah, Costa, Giuliano, Elsaify, Sameh, Pilgrim, Thomas, le Breton, Hervé, Urena, Marina, Muñoz-Garcia, Antonio Jesus, Sondergaard, Lars, Bach-Oller, Montserrat, Fraccaro, Chiara, Eltchaninoff, Hélène, Metz, Damien, Tamargo, Maria, Fradejas-Sastre, Victor, Rognoni, Andrea, Bruno, Francesco, Goliasch, Georg, Santaló-Corcoy, Marcelo, Jimenez-Mazuecos, Jesus, Webb, John G, Muntané-Carol, Guillem, Paradis, Jean-Michal, Mangieri, Antonio, Ribeiro, Henrique Barbosa, Campelo-Parada, Francisco, Rodés-Cabau, Josep
• Format: Article
• Language: English
• Subjects: Life Sciences
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2021.03.014

Among patients with acute coronary syndrome following transcatheter aortic valve replacement (TAVR), those presenting with ST-segment elevation myocardial infarction (STEMI) are at highest risk. The goal of this study was to determine the clinical characteristics, management, and outcomes of STEMI after TAVR. This was a multicenter study including 118 patients presenting with STEMI at a median of 255 days (interquartile range: 9 to 680 days) after TAVR. Procedural features of STEMI after TAVR managed with primary percutaneous coronary intervention (PCI) were compared with all-comer STEMI: 439 non-TAVR patients who had primary PCI within the 2 weeks before and after each post-TAVR STEMI case in 5 participating centers from different countries. Median door-to-balloon time was higher in TAVR patients (40 min [interquartile range: 25 to 57 min] vs. 30 min [interquartile range: 25 to 35 min]; p = 0.003). Procedural time, fluoroscopy time, dose-area product, and contrast volume were also higher in TAVR patients (p