Smoking and Cannabis Use among Childhood Cancer Survivors: Results of the French Childhood Cancer Survivor Study

• Published in: Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2021-10, Vol.30 (10), p.1965-1973
• Main Authors: Bougas, Nicolas, Fresneau, Brice, Pinto, Sandrine, Mayet, Aurélie, Marchi, Joffrey, Pein, François, Mansouri, Imene, Journy, Neige M Y, Jackson, Angela, Souchard, Vincent, Demoor-Goldschmidt, Charlotte, Vu-Bezin, Giao, Rubino, Carole, Oberlin, Odile, Haddy, Nadia, de Vathaire, Florent, Allodji, Rodrigue S, Dumas, Agnès
• Format: Article
• Language: English
• Subjects: Adult; Cancer Survivors - statistics & numerical data; Case-Control Studies; Cigarette Smoking - epidemiology; Cohort Studies; Female; France; Humans; Life Sciences; Male; Marijuana Smoking - epidemiology; Santé publique et épidémiologie; Smoking; Surveys and Questionnaires
• ISSN: 1055-9965; 1538-7755
• DOI: 10.1158/1055-9965.EPI-21-0193

Unhealthy behaviors among childhood cancer survivors increase the risks for cancer treatment adverse effects. We aimed to assess tobacco and cannabis use prevalence in this population and to identify factors associated with these consumptions. This study involved 2,887 5-year survivors from the French childhood cancer survivor study (FCCSS) cohort. Data on health behaviors were compared with those of controls from the general population. Associations of current smoking and cannabis use with clinical features, sociodemographic characteristics, and health-related quality of life (QOL) were investigated using multivariable logistic regressions. Prevalence for tobacco use was lower in survivors (26%) than in controls (41%, < 0.001). Among current smokers, survivors smoked more cigarettes per day and started at a younger age than controls. Women, college graduates, older, married, and CNS tumor survivors, as well as those who received chemotherapy and thoracic radiation therapy, were less likely to be smokers and/or cannabis consumers than others. Participants with a poor mental QOL were more likely to smoke. Preventive interventions and cessation programs must be carried out as early as possible in survivors' life, especially among young males with low educational level and poor mental health. This study brings new insights to health behaviors among childhood cancer survivors from a population with high rates of smoking and cannabis use.