Paroxysmal strabismus and stridor acquired in childhood: Do not overlook calcemia

Hypocalcemia is known to induce stridor but was rarely reported to cause strabismus. We report the case of a 4-year-old girl who presented with paroxysmal stridor and strabismus with diplopia, persisting for several weeks. Severe hypocalcemia (1.25 mmol/L) was finally diagnosed and was related to hy...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2020-02, Vol.27 (2), p.104-106
Main Authors: Escudier, A., Giabicani, E., Neven, B., Gouache, E., Blanchard, M., Isapof, A., Nougues, M.-C., Freihuber, C.
Format: Article
Language:English
Subjects:
APECED
Diplopia
Hypocalcemia
Hypoparathyroidism
Life Sciences
Ophthalmoparesis
Strabismus
Stridor
Vocal cord paresis
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Summary:Hypocalcemia is known to induce stridor but was rarely reported to cause strabismus. We report the case of a 4-year-old girl who presented with paroxysmal stridor and strabismus with diplopia, persisting for several weeks. Severe hypocalcemia (1.25 mmol/L) was finally diagnosed and was related to hypoparathyroidism, which was the first manifestation of autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED) in this patient. Strabismus and stridor both resolved after normalization of calcemia. This case report is a rare observation of paroxysmal strabismus caused by hypocalcemia and it highlights the importance of calcium monitoring in any situation of atypical neurological symptoms.
ISSN:0929-693X
1769-664X
DOI:10.1016/j.arcped.2019.12.006