Recent advances in the application of acetophenone in heterocyclic compounds synthesis

Acetophenone is an interesting synthon in the most organic reactions. Acetophenone has been utilized in the synthesis of many heterocyclic compounds. Acetophenone and most of its derivatives are commercially available or readily accessible and hence are ideal synthon for multicomponent reactions inc...

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Bibliographic Details
Published in:Journal of the Iranian Chemical Society 2020-02, Vol.17 (2), p.247-282
Main Authors: Mohammadi Ziarani, Ghodsi, Kheilkordi, Zohreh, Mohajer, Fatemeh
Format: Article
Language:English
Subjects:
Acetophenone
Analytical Chemistry
Biochemistry
Chemical Sciences
Chemical synthesis
Chemistry
Chemistry and Materials Science
Heterocyclic compounds
Inorganic Chemistry
Organic Chemistry
Physical Chemistry
Review
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Summary:Acetophenone is an interesting synthon in the most organic reactions. Acetophenone has been utilized in the synthesis of many heterocyclic compounds. Acetophenone and most of its derivatives are commercially available or readily accessible and hence are ideal synthon for multicomponent reactions including the three- and four-component reactions. Also, the biological activities of some compounds were studied. Herein, we want to review the application of the acetophenone as starting material in the synthesis of various heterocyclic compounds including fused and five-, six-, seven-membered rings via multicomponent reactions. Graphic abstract
ISSN:1735-207X
1735-2428
DOI:10.1007/s13738-019-01774-4