Demonstration of the yeasticidal efficacy of povidone-iodine–based commercial antiseptic solutions against Candida auris

Candida auris is an emerging yeast pathogen with worldwide distribution and a great propensity for nosocomial spread. Recent reports have warned of the significant emergence of C. auris in several healthcare facilities. In order to stop its nosocomial transmission, use of antiseptics constitutes the...

Full description

Saved in:
Bibliographic Details
Published in:Journal de mycologie médicale 2021-12, Vol.31 (4), p.101173-101173, Article 101173
Main Authors: Chesnay, Adélaïde, Bailly, Éric, Desoubeaux, Guillaume
Format: Article
Language:English
Subjects:
Anti-Infective Agents, Local - pharmacology
Candida
Candida albicans
Candida auris
Chemical Sciences
EN 1275
Human health and pathology
Infectious diseases
Life Sciences
Medicinal Chemistry
Microbiology and Parasitology
Mycology
Povidone-iodine
Povidone-Iodine - pharmacology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Candida auris is an emerging yeast pathogen with worldwide distribution and a great propensity for nosocomial spread. Recent reports have warned of the significant emergence of C. auris in several healthcare facilities. In order to stop its nosocomial transmission, use of antiseptics constitutes the first-line lever of action in the fighting against C. auris skin colonization. However, little is known about the efficacy of these products, and moreover no antiseptics are currently registered for use against C. auris. This study investigated the in vitro yeasticidal activity of povidone-iodine against C. auris, and compared the findings to C. albicans and C. glabrata, according to the EN standard 1275:2005. Results support the use of such commercial antiseptics in the context of colonization with this yeast.
ISSN:1156-5233
1773-0449
DOI:10.1016/j.mycmed.2021.101173