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Plasma levels of SAA1 and mortality after exposure to high-dose radiation

Presented in Annals of Translational Medicine, Jinfeng Huang and colleagues’ study (1) of the association between tissue/plasma levels of the serum amyloid A1 (SAA1) protein and dose of acute ionizing radiation exposure, highlights the potential benefits of SAA1 monitoring for triage purposes during...

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Bibliographic Details
Published in:Annals of translational medicine 2020, Vol.8 (11)
Main Author: Klokov, Dmitry
Format: Article
Language:English
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Summary:Presented in Annals of Translational Medicine, Jinfeng Huang and colleagues’ study (1) of the association between tissue/plasma levels of the serum amyloid A1 (SAA1) protein and dose of acute ionizing radiation exposure, highlights the potential benefits of SAA1 monitoring for triage purposes during potential mass-casualty events of exposure of humans to unknown doses of ionizing radiation. Two relatively separate potential utilities of measuring SAA1 in high-dose radiation exposed humans are proposed and discussed by the authors: one is reconstruction of exposure dose and second is prediction of adverse health outcome.
ISSN:2305-5839
2305-5839
DOI:10.21037/atm.2020.03.172