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CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair

DNA lesions block cellular processes such as transcription, inducing apoptosis, tissue failures, and premature aging. To counteract the deleterious effects of DNA damage, cells are equipped with various DNA repair pathways.

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Published in:Molecular and cellular biology 2019-03, Vol.39 (6)
Main Authors: Donnio, Lise-Marie, Lagarou, Anna, Sueur, Gabrielle, Mari, Pierre-Olivier, Giglia-Mari, Giuseppina
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Language:English
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container_issue 6
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container_title Molecular and cellular biology
container_volume 39
creator Donnio, Lise-Marie
Lagarou, Anna
Sueur, Gabrielle
Mari, Pierre-Olivier
Giglia-Mari, Giuseppina
description DNA lesions block cellular processes such as transcription, inducing apoptosis, tissue failures, and premature aging. To counteract the deleterious effects of DNA damage, cells are equipped with various DNA repair pathways.
doi_str_mv 10.1128/mcb.00225-18
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subjects Life Sciences
title CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair
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