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Surfactant micelle self-assembly directed highly symmetric ultrasmall inorganic cages
Nanoscale objects with highly symmetrical cage-like polyhedral shapes, often with icosahedral symmetry, have recently been assembled using DNA 1-3 , RNA 4 , and proteins 5,6 for biomedical applications. These achievements relied on advances in the development of programmable self-assembling biomater...
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Published in: | Nature (London) 2018-06, Vol.558, p.577-580 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | Nanoscale objects with highly symmetrical cage-like polyhedral shapes, often with icosahedral symmetry, have recently been assembled using DNA 1-3 , RNA 4 , and proteins 5,6 for biomedical applications. These achievements relied on advances in the development of programmable self-assembling biomaterials 7-10 , as well as rapidly developing single-particle three-dimensional (3D) reconstruction techniques of cryo electron microscopy (cryo-EM) images that provide high-resolution structural characterization of biological complexes 11-13. In contrast, such single-particle 3D |
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ISSN: | 0028-0836 1476-4687 |
DOI: | 10.1038/s41586-018-0221-0 |