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Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from Aspergillus Section Fumigati

The antifungal susceptibility of Aspergillus cryptic species is poorly known. We assessed 51 isolates, belonging to seven Fumigati cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drug...

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Bibliographic Details
Published in:Antimicrobial agents and chemotherapy 2020-11, Vol.64 (12)
Main Authors: Imbert, S., Normand, A., Cassaing, S., Gabriel, F., Kristensen, L., Bonnal, C., Lachaud, L., Costa, D., Guitard, Juliette, Hasseine, L., Palous, M., Piarroux, M., Hendrickx, M., Piarroux, R., Fekkar, A.
Format: Article
Language:English
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Summary:The antifungal susceptibility of Aspergillus cryptic species is poorly known. We assessed 51 isolates, belonging to seven Fumigati cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drugs, except for Aspergillus hiratsukae and Aspergillus tsurutae , and high MICs for amphotericin B for Aspergillus lentulus and Aspergillus udagawae .
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.01374-20