The transcriptomic analysis of Planorbarius corneus hemocytes (Gastropoda) naturally infected with Bilharziella polonica (Schistosomatidae)

The study of molluscan innate immunity is essential for understanding the evolution of the immune system. An advance in the knowledge of their immune system can be achieved by increasing the number of model species. Our study focuses on the immunity of Planorbarius corneus, a pulmonate snail widely...

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Bibliographic Details
Published in:Developmental and comparative immunology 2023-03, Vol.140, p.104607-104607, Article 104607
Main Authors: Orlov, I.A., Ataev, G.L., Gourbal, B., Tokmakova, A.S., Bobrovskaya, A.V., Prokhorova, E.E.
Format: Article
Language:English
Subjects:
Animal biology
Animals
Bilharziella polonica
Gastropoda - genetics
Hemocytes
Immune reactions
Immunology
Innate immunity
Invertebrate Zoology
Life Sciences
Natural invasion
Planorbarius corneus
Schistosomatidae
Snails
Transcriptome
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Summary:The study of molluscan innate immunity is essential for understanding the evolution of the immune system. An advance in the knowledge of their immune system can be achieved by increasing the number of model species. Our study focuses on the immunity of Planorbarius corneus, a pulmonate snail widely distributed in Eurasia. These snails are intermediate hosts of many trematodes, including Bilharziella polonica (Schistosomatidae). In this paper we obtained and analyzed transcriptomes of hemocytes of uninfected snails Planorbarius corneus and snails naturally infected with Bilharziella polonica. The transcriptomes were found to contain transcripts encoding all major groups of immune factors previously described for other gastropods. Pathogen-recognition molecules were the most diverse group of immune factors. Comparison of the transcriptomes of the infected and the uninfected molluscs showed that the expression of some genes changed during infection. Our results extend the knowledge of immune responses of pulmonate snails to trematode invasion and promote P. corneus as a new model for the study of molluscan defence reactions. •The first study of Planorbarius corneus hemocytes transcriptome.•Transcripts encoding representatives of all main groups of innate immunity factors are detected.•PRR is the most diverse group of immune factors in snails hemocytes.•Infection with Bilharziella polonica changes expression of some genes in hemocytes.
ISSN:0145-305X
1879-0089
DOI:10.1016/j.dci.2022.104607