Synthesis and Antifungal Activity of Novel Bisdithiocarbamate Derivatives of Carbohydrates against Fusarium oxysporum f. sp. l ini

Novel carbamic esters possessing a carbohydrate moiety derived from glycerol or d-glucose with two N,N-diethyldithiocarbamoyl groups and a series of bisdithiocarbamic esters having a ketone or an alkyl ester have been synthesized. The in vitro activity of these new compounds was evaluated against Fu...

Full description

Saved in:
Bibliographic Details
Published in:Journal of agricultural and food chemistry 2000-11, Vol.48 (11), p.5283-5287
Main Authors: Rafin, Catherine, Veignie, Etienne, Sancholle, Michel, Postel, Denis, Len, Christophe, Villa, Pierre, Ronco, Gino
Format: Article
Language:English
Subjects:
Chemical Sciences
Environmental Sciences
Life Sciences
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Novel carbamic esters possessing a carbohydrate moiety derived from glycerol or d-glucose with two N,N-diethyldithiocarbamoyl groups and a series of bisdithiocarbamic esters having a ketone or an alkyl ester have been synthesized. The in vitro activity of these new compounds was evaluated against Fusarium oxysporum f. sp. lini. Some of the compounds [bis[1,3-S-(N,N-diethyldithiocarbamoyl)]-1,3-dideoxyglycerol) and diethyl N,N ‘-(1,3-dideoxyglycer-1,3-diyl)bis(dithiocarbamate)] were more active for inhibiting vegetative mycelium growth than, respectively, the commercial N,N-diethyldithiocarbamic acid sodium salt and Maneb. The structure activity of these new compounds is discussed. Keywords: Bis(1,3-dithiocarbamoyl)-1,3-dideoxyglycerol; flax; in vitro antifungal activity; Fusarium oxysporum
ISSN:0021-8561
1520-5118
DOI:10.1021/jf0003698