Surface Modification of Brass via Ultrashort Pulsed Direct Laser Interference Patterning and Its Effect on Bacteria-Substrate Interaction

In recent decades, antibiotic resistance has become a crucial challenge for human health. One potential solution to this problem is the use of antibacterial surfaces, i.e., copper and copper alloys. This study investigates the antibacterial properties of brass that underwent topographic surface func...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2023-08, Vol.15 (30), p.36908-36921
Main Authors: Ahmed, Aisha Saddiqa, Müller, Daniel Wyn, Bruyere, Stephanie, Holtsch, Anne, Müller, Frank, Barrirero, Jenifer, Brix, Kristina, Migot, Sylvie, Kautenburger, Ralf, Jacobs, Karin, Pierson, Jean-François, Mücklich, Frank
Format: Article
Language:English
Subjects:
Alloys - chemistry
Alloys - pharmacology
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Bacteria
Chemical Sciences
Copper - chemistry
Copper - pharmacology
Escherichia coli
Humans
Lasers
Material chemistry
Surface Properties
Surfaces, Interfaces, and Applications
Zinc - chemistry
Zinc - pharmacology
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Summary:In recent decades, antibiotic resistance has become a crucial challenge for human health. One potential solution to this problem is the use of antibacterial surfaces, i.e., copper and copper alloys. This study investigates the antibacterial properties of brass that underwent topographic surface functionalization via ultrashort pulsed direct laser interference patterning. Periodic line-like patterns in the scale range of single bacterial cells were created on brass with a 37% zinc content to enhance the contact area for rod-shaped Escherichia coli (E. coli). Although the topography facilitates attachment of bacteria to the surface, reduced killing rates for E. coli are observed. In parallel, a high-resolution methodical approach was employed to explore the impact of laser-induced topographical and chemical modifications on the antibacterial properties. The findings reveal the underlying role of the chemical modification concerning the antimicrobial efficiency of the Cu-based alloy within the superficial layers of a few hundred nanometers. Overall, this study provides valuable insight into the effect of alloy composition on targeted laser processing for antimicrobial Cu-surfaces, which facilitates the thorough development and optimization of the process concerning antimicrobial applications.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.3c04801