Cushing's syndrome in the elderly: data from the European Registry on Cushing's syndrome

To evaluate whether age-related differences exist in clinical characteristics, diagnostic approach, and management strategies in patients with Cushing's syndrome (CS) included in the European Registry on Cushing's Syndrome (ERCUSYN). Cohort study. We analyzed 1791 patients with CS, of whom...

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Published in:European journal of endocrinology 2023-04, Vol.188 (4), p.395-406
Main Authors: Amodru, Vincent, Ferriere, Amandine, Tabarin, Antoine, Castinetti, Frederic, Tsagarakis, Stylianos, Toth, Miklos, Feelders, Richard A, Webb, Susan M, Reincke, Martin, Netea-Maier, Romana, Kastelan, Darko, Elenkova, Atanaska, Maiter, Dominique, Ragnarsson, Oskar, Santos, Alicia, Valassi, Elena
Format: Article
Language:English
Subjects:
Aged
Cohort Studies
Cushing Syndrome - diagnosis
Human health and pathology
Humans
Hydrocortisone
Life Sciences
Male
Pituitary ACTH Hypersecretion
Registries
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Summary:To evaluate whether age-related differences exist in clinical characteristics, diagnostic approach, and management strategies in patients with Cushing's syndrome (CS) included in the European Registry on Cushing's Syndrome (ERCUSYN). Cohort study. We analyzed 1791 patients with CS, of whom 1234 (69%) had pituitary-dependent CS (PIT-CS), 450 (25%) adrenal-dependent CS (ADR-CS), and 107 (6%) had an ectopic source (ECT-CS). According to the WHO criteria, 1616 patients (90.2%) were classified as younger (
ISSN:0804-4643
1479-683X
DOI:10.1093/ejendo/lvad008