Clinical value of automated fibrin generation markers in patients with septic shock: a SepsiCoag ancillary study

Summary An ancillary analysis to the SepsiCoag multicentric prospective observational study on patients entering an intensive care unit with septic shock evaluated the prognostic potential of fibrin generation markers ( FGM s) tested at inclusion in the study, on survival at day 30. After centraliza...

Full description

Saved in:
Bibliographic Details
Published in:British journal of haematology 2018-09, Vol.183 (4), p.636-647
Main Authors: Gris, Jean‐christophe, Cochery-Nouvellon, Eva, Bouvier, Sylvie, Jaber, Samir, Albanese, Jacques, Constantin, Jean‐michel, Orban, Jean‐christophe, Morel, Jérôme, Leone, Marc, Deras, Pauline, Elotmani, Loubna, Lavigne-Lissalde, Géraldine, Lefrant, Jean‐yves
Format: Article
Language:English
Subjects:
Hematology
Human health and pathology
Life Sciences
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary An ancillary analysis to the SepsiCoag multicentric prospective observational study on patients entering an intensive care unit with septic shock evaluated the prognostic potential of fibrin generation markers ( FGM s) tested at inclusion in the study, on survival at day 30. After centralization of samples, three automated FGM s were compared: D‐dimers (DDi), fibrin/fibrinogen degradation products ( FDP ) and fibrin monomers ( FM ). FM was the single FGM that was significantly higher in non‐surviving patients, area under the receiver‐operator characteristic curve (AUC ROC ): 0·617, P
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.15576