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Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings

Experimental systems that faithfully replicate human physiology at cellular, tissue and organ level are crucial to the development of efficacious and safe therapies with high success rates and low cost. The development of such systems is challenging and requires skills, expertise and inputs from a d...

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Published in:Alternatives to laboratory animals 2021-05, Vol.49 (3), p.93-110
Main Authors: Singh, Bhumika, Abdelgawad, Mohamed Essameldin, Ali, Zulfiqur, Bailey, Jarrod, Budyn, Elisa, Civita, Prospero, Clift, Martin J.D., Connelly, John T., Constant, Samuel, Hittinger, Marius, Kandarova, Helena, Kearns, Victoria Rosalind, Kiuru, Tony, Kostrzewski, Tomasz, Kress, Sebastian, Durban, Victoria Marsh, Lehr, Claus-Michael, McMillan, Hayley, Metz, Julia Katharina, Monteban, Vivian, Movia, Dania, Neto, Catia, Owen, Carla, Paasonen, Lauri, Palmer, Kerri Anne, Pilkington, Geoffrey John, Pilkington, Karen, Prina-Mello, Adriele, Roper, Clive, Sheard, Jonathan, Smith, Sheree, Turner, Janette Ellen, Roy, Ipsita, Tutty, Melissa Anne, Velliou, Eirini, Wilkinson, John Malcolm
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container_title Alternatives to laboratory animals
container_volume 49
creator Singh, Bhumika
Abdelgawad, Mohamed Essameldin
Ali, Zulfiqur
Bailey, Jarrod
Budyn, Elisa
Civita, Prospero
Clift, Martin J.D.
Connelly, John T.
Constant, Samuel
Hittinger, Marius
Kandarova, Helena
Kearns, Victoria Rosalind
Kiuru, Tony
Kostrzewski, Tomasz
Kress, Sebastian
Durban, Victoria Marsh
Lehr, Claus-Michael
McMillan, Hayley
Metz, Julia Katharina
Monteban, Vivian
Movia, Dania
Neto, Catia
Owen, Carla
Paasonen, Lauri
Palmer, Kerri Anne
Pilkington, Geoffrey John
Pilkington, Karen
Prina-Mello, Adriele
Roper, Clive
Sheard, Jonathan
Smith, Sheree
Turner, Janette Ellen
Roy, Ipsita
Tutty, Melissa Anne
Velliou, Eirini
Wilkinson, John Malcolm
description Experimental systems that faithfully replicate human physiology at cellular, tissue and organ level are crucial to the development of efficacious and safe therapies with high success rates and low cost. The development of such systems is challenging and requires skills, expertise and inputs from a diverse range of experts, such as biologists, physicists, engineers, clinicians and regulatory bodies. Kirkstall Limited, a biotechnology company based in York, UK, organised the annual conference, Advances in Cell and Tissue Culture (ACTC), which brought together people having a variety of expertise and interests, to present and discuss the latest developments in the field of cell and tissue culture and in vitro modelling. The conference has also been influential in engaging animal welfare organisations in the promotion of research, collaborative projects and funding opportunities. This report describes the proceedings of the latest ACTC conference, which was held virtually on 30th September and 1st October 2020, and included sessions on in vitro models in the following areas: advanced skin and respiratory models, neurological disease, cancer research, advanced models including 3-D, fluid flow and co-cultures, diabetes and other age-related disorders, and animal-free research. The roundtable session on the second day was very interactive and drew huge interest, with intriguing discussion taking place among all participants on the theme of replacement of animal models of disease.
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title Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings
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