Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)

• Published in: Pure and applied chemistry 2011-02, Vol.83 (5), p.1129-1158
• Main Authors: Proudfoot, John, Nosjean, Olivier, Blanchard, Jan, Wang, John, Besson, Dominique, Crankshaw, Denis, Gauglitz, Günter, Hertzberg, Robert, Homon, Carol, Llewellyn, Lyndon, Neubig, Richard, Walker, Larry, Villa, Pascal
• Format: Article
• Language: English
• Subjects: assay types; Biochemistry, Molecular Biology; biomolecular screening; data handling; drug discovery; glossary; IUPAC Chemistry and Human Health Division; Life Sciences; Screening
• ISSN: 0033-4545; 1365-3075
• DOI: 10.1351/PAC-REC-09-05-03

Biomolecular screening is now a crucial component of the drug discovery process, and this glossary will be of use to practitioners in the field of screening and to those who interact with the screening community. The glossary contains definitions related to various aspects of the screening process such as assay types, data handling, and relevant technologies. Many of the terms used in this discipline are not covered by existing glossaries, and where they are, the definitions are often not appropriate for this field. Where appropriate, this document provides new or modified definitions to better reflect the new context. The field of biomolecular screening is multidisciplinary in nature, and this glossary, containing authoritative definitions, will be useful not only for regular practitioners, but also for those who make use of data generated during the screening process.