An Expression Quantitative Trait Locus of Fc Gamma Receptor Genes is Associated with Anti-Malarial IgG Responses and Infection Levels in Burkinabe Families Running Title: Association of rs1771575 with Malaria

This study identifies the non-coding variant rs1771575 in the FCGR gene cluster as a key marker for IgG levels and malaria infection in children. It highlights the role of regulatory and coding variants in shaping immune responses to Plasmodium falciparum.

Saved in:
Bibliographic Details
Published in:The Journal of infectious diseases 2024, Vol.24 (21)
Main Authors: Cretin, Jules, Adjemout, Mathieu, Dieppois, Christelle, Gallardo, Frederic, Torres, Magali, Merard, Zachary, Sawadogo, Serge Aimé, Picard, Christophe, Rihet, Pascal, Paul, Pascale
Format: Article
Language:English
Subjects:
Life Sciences
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study identifies the non-coding variant rs1771575 in the FCGR gene cluster as a key marker for IgG levels and malaria infection in children. It highlights the role of regulatory and coding variants in shaping immune responses to Plasmodium falciparum.
ISSN:0022-1899
1537-6613
DOI:10.3390/ijms242115711