Management of neonates exposed prenatally to opioids: Impact of a developmental care program implementation

Traditional approaches to management of neonates prenatally exposed to opioids are based on the use of pharmacotherapy (PT), adjusted to evolution of infant symptoms. Newer approaches focused on non-pharmacological care (NPC) are emerging, but there is little evidence on the active policies to imple...

Full description

Saved in:
Bibliographic Details
Published in:Early human development 2024-11, Vol.198 (1), p.106132, Article 106132
Main Authors: Cambonie, Gilles, Aujogues dit Baron, Lison, Combes, Clementine, Chanal, Corinne, Mazurier, Evelyne, Toubin, Rose-Marie, Fortier, Mathilde, Polito, Angelo, Fuchs, Florent, Gavotto, Arthur
Format: Article
Language:English
Subjects:
Complementary therapies
Life Sciences
Neonatal abstinence syndrome
Opioids
Pharmacotherapy
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Traditional approaches to management of neonates prenatally exposed to opioids are based on the use of pharmacotherapy (PT), adjusted to evolution of infant symptoms. Newer approaches focused on non-pharmacological care (NPC) are emerging, but there is little evidence on the active policies to implement to ensure their widespread practice. The primary objective of the study was to assess whether the implementation of a developmental care program in our neonatal medicine department had an impact on the management of these infants during hospitalization, notably exposure to NPC. Observational study in a tertiary perinatal center. Data collected during hospitalization for infants with in utero opioid exposure included admission in the parents-infant unit (PIU) of the maternity ward, exposure to NPC and PT, occurrence of neonatal opioid withdrawal syndrome (NOWS), length of hospital stay (LOS) and feeding type at discharge. The impact of the intervention was measured by comparing three 6-year periods, the first preceding the implementation of a formalized developmental care program (2003–2008); the second following implementation of the program (2009–2014); the third after consolidation of the program (2015–2020). 258 infants prenatally exposed to opioid were recorded. From the first to the third period, admission rate in the PIU was comparable (68 % to 73 %, p = 0. 95). Exposure to NPC (37 % to 84 %, p 
ISSN:0378-3782
1872-6232
1872-6232
DOI:10.1016/j.earlhumdev.2024.106132