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Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial
Aim The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpit...
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Published in: | International endodontic journal 2023-08, Vol.56 (8), p.922-931 |
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container_title | International endodontic journal |
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creator | Gaudin, Alexis Clouet, Roselyne Boëffard, Camille Laham, Amany Martin, Hamida Amador Del Valle, Gilles Enkel, Bénédicte Prud'homme, Tony |
description | Aim
The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP).
Methodology
The study protocol was registered with ClinicalTrials.gov (NCT03802305).
In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days.
Results
The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p > .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%).
Conclusions
This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar. |
doi_str_mv | 10.1111/iej.13935 |
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The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP).
Methodology
The study protocol was registered with ClinicalTrials.gov (NCT03802305).
In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days.
Results
The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p > .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%).
Conclusions
This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</description><identifier>ISSN: 0143-2885</identifier><identifier>EISSN: 1365-2591</identifier><identifier>DOI: 10.1111/iej.13935</identifier><identifier>PMID: 37209243</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Anesthesia ; Anesthesia, Dental ; Anesthetics, Local ; Blood pressure ; dental anaesthesia ; dental emergency ; Double-Blind Method ; Heart rate ; Human health and pathology ; Humans ; Lidocaine ; Life Sciences ; local anaesthesia ; Local anesthesia ; Mandible ; mandibular molars ; Mandibular Nerve ; Nerve Block ; Oxygen saturation ; pain management ; Prospective Studies ; Pulpitis ; pulpotomy ; Statistical analysis ; symptomatic irreversible pulpitis</subject><ispartof>International endodontic journal, 2023-08, Vol.56 (8), p.922-931</ispartof><rights>2023 British Endodontic Society. Published by John Wiley & Sons Ltd</rights><rights>2023 British Endodontic Society. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2023 International Endodontic Journal. Published by John Wiley & Sons Ltd.</rights><rights>Copyright</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293</citedby><cites>FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293</cites><orcidid>0000-0003-4139-8927</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37209243$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://nantes-universite.hal.science/hal-04802923$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Gaudin, Alexis</creatorcontrib><creatorcontrib>Clouet, Roselyne</creatorcontrib><creatorcontrib>Boëffard, Camille</creatorcontrib><creatorcontrib>Laham, Amany</creatorcontrib><creatorcontrib>Martin, Hamida</creatorcontrib><creatorcontrib>Amador Del Valle, Gilles</creatorcontrib><creatorcontrib>Enkel, Bénédicte</creatorcontrib><creatorcontrib>Prud'homme, Tony</creatorcontrib><title>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</title><title>International endodontic journal</title><addtitle>Int Endod J</addtitle><description>Aim
The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP).
Methodology
The study protocol was registered with ClinicalTrials.gov (NCT03802305).
In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days.
Results
The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p > .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%).
Conclusions
This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</description><subject>Anesthesia</subject><subject>Anesthesia, Dental</subject><subject>Anesthetics, Local</subject><subject>Blood pressure</subject><subject>dental anaesthesia</subject><subject>dental emergency</subject><subject>Double-Blind Method</subject><subject>Heart rate</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Lidocaine</subject><subject>Life Sciences</subject><subject>local anaesthesia</subject><subject>Local anesthesia</subject><subject>Mandible</subject><subject>mandibular molars</subject><subject>Mandibular Nerve</subject><subject>Nerve Block</subject><subject>Oxygen saturation</subject><subject>pain management</subject><subject>Prospective Studies</subject><subject>Pulpitis</subject><subject>pulpotomy</subject><subject>Statistical analysis</subject><subject>symptomatic irreversible pulpitis</subject><issn>0143-2885</issn><issn>1365-2591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kc1uEzEUhS0EoiGw4AWQJTZlMa1_5sfDLooKbRWJDawtj-eaOHjGg-1JFV6I18RpSish4Y2tcz-de30PQm8puaD5XFrYXVDe8uoZWlBeVwWrWvocLQgtecGEqM7Qqxh3hJCKcPoSnfGGkZaVfIF-r_0wqWDH79iOKSgfI_g5Yp3lOUGwv6DHalQQ0xaiVfjOpm1GTS75gJXbg3cq4BHCHnDnvP6RqzjDOAVQaYAxYW9wPAxT8oNKVmMbAuwhRNs5wNPsJpts_IhXOKix98N9S-3zNN65_EzBKvcavTDKRXjzcC_Rt09XX9fXxebL55v1alNoLpqqaIwmwKBjba8UMaDbmhhNu1oYUdNOtG3f0Cw0NS17LaDkoueNYhpKwQ1r-RJ9OPlulZNTsIMKB-mVlderjTxqpBSEtYzvaWbPT-wU_M85b0gONmpwTo3HHUomaN3kJLL1Er3_B935OYz5J5niFaUNoeypuQ45hwDmcQJK5DFpmZOW90ln9t2D49wN0D-Sf6PNwOUJuLMODv93kjdXtyfLP8fgtnA</recordid><startdate>202308</startdate><enddate>202308</enddate><creator>Gaudin, Alexis</creator><creator>Clouet, Roselyne</creator><creator>Boëffard, Camille</creator><creator>Laham, Amany</creator><creator>Martin, Hamida</creator><creator>Amador Del Valle, Gilles</creator><creator>Enkel, Bénédicte</creator><creator>Prud'homme, Tony</creator><general>Wiley Subscription Services, Inc</general><general>Wiley</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0003-4139-8927</orcidid></search><sort><creationdate>202308</creationdate><title>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</title><author>Gaudin, Alexis ; Clouet, Roselyne ; Boëffard, Camille ; Laham, Amany ; Martin, Hamida ; Amador Del Valle, Gilles ; Enkel, Bénédicte ; Prud'homme, Tony</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anesthesia</topic><topic>Anesthesia, Dental</topic><topic>Anesthetics, Local</topic><topic>Blood pressure</topic><topic>dental anaesthesia</topic><topic>dental emergency</topic><topic>Double-Blind Method</topic><topic>Heart rate</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Lidocaine</topic><topic>Life Sciences</topic><topic>local anaesthesia</topic><topic>Local anesthesia</topic><topic>Mandible</topic><topic>mandibular molars</topic><topic>Mandibular Nerve</topic><topic>Nerve Block</topic><topic>Oxygen saturation</topic><topic>pain management</topic><topic>Prospective Studies</topic><topic>Pulpitis</topic><topic>pulpotomy</topic><topic>Statistical analysis</topic><topic>symptomatic irreversible pulpitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gaudin, Alexis</creatorcontrib><creatorcontrib>Clouet, Roselyne</creatorcontrib><creatorcontrib>Boëffard, Camille</creatorcontrib><creatorcontrib>Laham, Amany</creatorcontrib><creatorcontrib>Martin, Hamida</creatorcontrib><creatorcontrib>Amador Del Valle, Gilles</creatorcontrib><creatorcontrib>Enkel, Bénédicte</creatorcontrib><creatorcontrib>Prud'homme, Tony</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>International endodontic journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gaudin, Alexis</au><au>Clouet, Roselyne</au><au>Boëffard, Camille</au><au>Laham, Amany</au><au>Martin, Hamida</au><au>Amador Del Valle, Gilles</au><au>Enkel, Bénédicte</au><au>Prud'homme, Tony</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</atitle><jtitle>International endodontic journal</jtitle><addtitle>Int Endod J</addtitle><date>2023-08</date><risdate>2023</risdate><volume>56</volume><issue>8</issue><spage>922</spage><epage>931</epage><pages>922-931</pages><issn>0143-2885</issn><eissn>1365-2591</eissn><abstract>Aim
The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP).
Methodology
The study protocol was registered with ClinicalTrials.gov (NCT03802305).
In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days.
Results
The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p > .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%).
Conclusions
This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>37209243</pmid><doi>10.1111/iej.13935</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-4139-8927</orcidid></addata></record> |
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source | Wiley-Blackwell Read & Publish Collection |
subjects | Anesthesia Anesthesia, Dental Anesthetics, Local Blood pressure dental anaesthesia dental emergency Double-Blind Method Heart rate Human health and pathology Humans Lidocaine Life Sciences local anaesthesia Local anesthesia Mandible mandibular molars Mandibular Nerve Nerve Block Oxygen saturation pain management Prospective Studies Pulpitis pulpotomy Statistical analysis symptomatic irreversible pulpitis |
title | Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial |
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