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Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial

Aim The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpit...

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Published in:International endodontic journal 2023-08, Vol.56 (8), p.922-931
Main Authors: Gaudin, Alexis, Clouet, Roselyne, Boëffard, Camille, Laham, Amany, Martin, Hamida, Amador Del Valle, Gilles, Enkel, Bénédicte, Prud'homme, Tony
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cited_by cdi_FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293
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container_end_page 931
container_issue 8
container_start_page 922
container_title International endodontic journal
container_volume 56
creator Gaudin, Alexis
Clouet, Roselyne
Boëffard, Camille
Laham, Amany
Martin, Hamida
Amador Del Valle, Gilles
Enkel, Bénédicte
Prud'homme, Tony
description Aim The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP). Methodology The study protocol was registered with ClinicalTrials.gov (NCT03802305). In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days. Results The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p > .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%). Conclusions This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.
doi_str_mv 10.1111/iej.13935
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Methodology The study protocol was registered with ClinicalTrials.gov (NCT03802305). In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days. Results The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p &gt; .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%). Conclusions This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</description><identifier>ISSN: 0143-2885</identifier><identifier>EISSN: 1365-2591</identifier><identifier>DOI: 10.1111/iej.13935</identifier><identifier>PMID: 37209243</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Anesthesia ; Anesthesia, Dental ; Anesthetics, Local ; Blood pressure ; dental anaesthesia ; dental emergency ; Double-Blind Method ; Heart rate ; Human health and pathology ; Humans ; Lidocaine ; Life Sciences ; local anaesthesia ; Local anesthesia ; Mandible ; mandibular molars ; Mandibular Nerve ; Nerve Block ; Oxygen saturation ; pain management ; Prospective Studies ; Pulpitis ; pulpotomy ; Statistical analysis ; symptomatic irreversible pulpitis</subject><ispartof>International endodontic journal, 2023-08, Vol.56 (8), p.922-931</ispartof><rights>2023 British Endodontic Society. Published by John Wiley &amp; Sons Ltd</rights><rights>2023 British Endodontic Society. Published by John Wiley &amp; Sons Ltd.</rights><rights>Copyright © 2023 International Endodontic Journal. Published by John Wiley &amp; Sons Ltd.</rights><rights>Copyright</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293</citedby><cites>FETCH-LOGICAL-c3875-7fc0e2eb29daa0fec960fc1b68f861b899d71fc17614dc8e438d37a2ce483f293</cites><orcidid>0000-0003-4139-8927</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37209243$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://nantes-universite.hal.science/hal-04802923$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Gaudin, Alexis</creatorcontrib><creatorcontrib>Clouet, Roselyne</creatorcontrib><creatorcontrib>Boëffard, Camille</creatorcontrib><creatorcontrib>Laham, Amany</creatorcontrib><creatorcontrib>Martin, Hamida</creatorcontrib><creatorcontrib>Amador Del Valle, Gilles</creatorcontrib><creatorcontrib>Enkel, Bénédicte</creatorcontrib><creatorcontrib>Prud'homme, Tony</creatorcontrib><title>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</title><title>International endodontic journal</title><addtitle>Int Endod J</addtitle><description>Aim The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP). Methodology The study protocol was registered with ClinicalTrials.gov (NCT03802305). In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days. Results The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p &gt; .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%). Conclusions This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</description><subject>Anesthesia</subject><subject>Anesthesia, Dental</subject><subject>Anesthetics, Local</subject><subject>Blood pressure</subject><subject>dental anaesthesia</subject><subject>dental emergency</subject><subject>Double-Blind Method</subject><subject>Heart rate</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Lidocaine</subject><subject>Life Sciences</subject><subject>local anaesthesia</subject><subject>Local anesthesia</subject><subject>Mandible</subject><subject>mandibular molars</subject><subject>Mandibular Nerve</subject><subject>Nerve Block</subject><subject>Oxygen saturation</subject><subject>pain management</subject><subject>Prospective Studies</subject><subject>Pulpitis</subject><subject>pulpotomy</subject><subject>Statistical analysis</subject><subject>symptomatic irreversible pulpitis</subject><issn>0143-2885</issn><issn>1365-2591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kc1uEzEUhS0EoiGw4AWQJTZlMa1_5sfDLooKbRWJDawtj-eaOHjGg-1JFV6I18RpSish4Y2tcz-de30PQm8puaD5XFrYXVDe8uoZWlBeVwWrWvocLQgtecGEqM7Qqxh3hJCKcPoSnfGGkZaVfIF-r_0wqWDH79iOKSgfI_g5Yp3lOUGwv6DHalQQ0xaiVfjOpm1GTS75gJXbg3cq4BHCHnDnvP6RqzjDOAVQaYAxYW9wPAxT8oNKVmMbAuwhRNs5wNPsJpts_IhXOKix98N9S-3zNN65_EzBKvcavTDKRXjzcC_Rt09XX9fXxebL55v1alNoLpqqaIwmwKBjba8UMaDbmhhNu1oYUdNOtG3f0Cw0NS17LaDkoueNYhpKwQ1r-RJ9OPlulZNTsIMKB-mVlderjTxqpBSEtYzvaWbPT-wU_M85b0gONmpwTo3HHUomaN3kJLL1Er3_B935OYz5J5niFaUNoeypuQ45hwDmcQJK5DFpmZOW90ln9t2D49wN0D-Sf6PNwOUJuLMODv93kjdXtyfLP8fgtnA</recordid><startdate>202308</startdate><enddate>202308</enddate><creator>Gaudin, Alexis</creator><creator>Clouet, Roselyne</creator><creator>Boëffard, Camille</creator><creator>Laham, Amany</creator><creator>Martin, Hamida</creator><creator>Amador Del Valle, Gilles</creator><creator>Enkel, Bénédicte</creator><creator>Prud'homme, Tony</creator><general>Wiley Subscription Services, Inc</general><general>Wiley</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0003-4139-8927</orcidid></search><sort><creationdate>202308</creationdate><title>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</title><author>Gaudin, Alexis ; 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Calcified Tissue Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>International endodontic journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gaudin, Alexis</au><au>Clouet, Roselyne</au><au>Boëffard, Camille</au><au>Laham, Amany</au><au>Martin, Hamida</au><au>Amador Del Valle, Gilles</au><au>Enkel, Bénédicte</au><au>Prud'homme, Tony</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial</atitle><jtitle>International endodontic journal</jtitle><addtitle>Int Endod J</addtitle><date>2023-08</date><risdate>2023</risdate><volume>56</volume><issue>8</issue><spage>922</spage><epage>931</epage><pages>922-931</pages><issn>0143-2885</issn><eissn>1365-2591</eissn><abstract>Aim The aim of this study was to compare the cardiovascular effects [heart rate, oxygen saturation (SpO2), systolic and diastolic blood pressure] and the anaesthetic efficacy of intraosseous computerized anaesthesia (ICA) versus inferior alveolar nerve block (IANB) in Symptomatic irreversible pulpitis (SIP). Methodology The study protocol was registered with ClinicalTrials.gov (NCT03802305). In a randomized, prospective clinical trial, 72 mandibular molar teeth with SIP were randomly allocated to conventional IANB injection (n = 36) or ICA injection (n = 36), both with 1.8 mL of 4% articaine with 1:100 000 epinephrine. The primary objective was to assess the cardiovascular parameters (heart rate, oxygen saturation, blood pressure) before, during and after the anaesthesia. The secondary objectives were to compare ICA with IANB for success and postoperative outcomes for up to 3 days. Results The maximum increase in heart rate in the ICA group was greater than in the IANB. Other cardiovascular parameters did not show differences throughout the clinical procedure. There were no statistically significant differences (p &gt; .05) between groups for sex, age, or anxiety. The total success rate of ICA (91.43%) was significantly higher (p = .0034) than that of IANB (69.44%). Conclusions This study establishes that ICA is safe and efficient in the first intention for the treatment of SIP of the mandibular molar.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>37209243</pmid><doi>10.1111/iej.13935</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-4139-8927</orcidid></addata></record>
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identifier ISSN: 0143-2885
ispartof International endodontic journal, 2023-08, Vol.56 (8), p.922-931
issn 0143-2885
1365-2591
language eng
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source Wiley-Blackwell Read & Publish Collection
subjects Anesthesia
Anesthesia, Dental
Anesthetics, Local
Blood pressure
dental anaesthesia
dental emergency
Double-Blind Method
Heart rate
Human health and pathology
Humans
Lidocaine
Life Sciences
local anaesthesia
Local anesthesia
Mandible
mandibular molars
Mandibular Nerve
Nerve Block
Oxygen saturation
pain management
Prospective Studies
Pulpitis
pulpotomy
Statistical analysis
symptomatic irreversible pulpitis
title Comparing intraosseous computerized anaesthesia with inferior alveolar nerve block in the treatment of symptomatic irreversible pulpitis: A randomized controlled trial
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