Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes

An efficient photochemical method for the site-specific immobilization and patterning of (bio)molecules inside glass capillary tubes is reported. The strategy involves the photodeprotection of reactive aminooxy groups on surfaces and subsequent reaction with aldehyde containing (bio)molecules.

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Bibliographic Details
Published in:Lab on a chip 2008-01, Vol.8 (12), p.2161-2163
Main Authors: Dendane, Nabil, Hoang, Antoine, Renaudet, Olivier, Vinet, Françoise, Dumy, Pascal, Defrancq, Eric
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Analytical chemistry
Capillary Action
Carbohydrate Sequence
Chemical Sciences
Electrophoresis, Capillary
Electrophoresis, Capillary - methods
Glass
Glass - chemistry
Microfluidics
Microfluidics - instrumentation
Microfluidics - methods
Molecular Sequence Data
Photochemistry
Silanes
Silanes - chemistry
Silicon Dioxide
Silicon Dioxide - chemistry
Surface Properties
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Description
Summary:An efficient photochemical method for the site-specific immobilization and patterning of (bio)molecules inside glass capillary tubes is reported. The strategy involves the photodeprotection of reactive aminooxy groups on surfaces and subsequent reaction with aldehyde containing (bio)molecules.
ISSN:1473-0197
1473-0189
DOI:10.1039/b811786a