MR elastography of liver tumours: value of viscoelastic properties for tumour characterisation

Objectives To assess the value of the viscoelastic parameters in the characterisation of liver tumours at MR elastography. Patients and methods Ninety-four patients with liver tumours >1 cm prospectively underwent MR elastography using 50-Hz mechanical waves and a full three-directional motion-se...

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Bibliographic Details
Published in:European radiology 2012-10, Vol.22 (10), p.2169-2177
Main Authors: Garteiser, Philippe, Doblas, Sabrina, Daire, Jean-Luc, Wagner, Mathilde, Leitao, Helena, Vilgrain, Valérie, Sinkus, Ralph, Van Beers, Bernard E.
Format: Article
Language:English
Subjects:
Adult
Aged
Bioengineering
Carcinoma, Hepatocellular - diagnosis
Contrast agents
Diagnostic Radiology
Elasticity Imaging Techniques - methods
Female
Hepatobiliary-Pancreas
Humans
Imaging
Internal Medicine
Interventional Radiology
Life Sciences
Liver cancer
Liver Neoplasms - diagnosis
Magnetic Resonance Imaging
Male
Mechanical properties
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Pathology
Prospective Studies
Radiology
Reproducibility of Results
Tumors
Ultrasound
Viscoelasticity
Viscosity
Young Adult
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Summary:Objectives To assess the value of the viscoelastic parameters in the characterisation of liver tumours at MR elastography. Patients and methods Ninety-four patients with liver tumours >1 cm prospectively underwent MR elastography using 50-Hz mechanical waves and a full three-directional motion-sensitive sequence. The model-free viscoelastic parameters (the complex shear modulus and its real and imaginary parts, i.e. the storage and loss moduli) were calculated in 72 lesions after exclusion of cystic, treated or histopathologically undetermined tumours. Results We observed higher absolute shear modulus and loss modulus in malignant versus benign tumours (3.38 ± 0.26 versus 2.41 ± 0.15 kPa, P  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-012-2474-6