Time trends in colorectal cancer early postoperative mortality. A French 25-year population-based study

Background Postoperative mortality after resection of colorectal cancer is an important issue. The aim of this study was to assess early postoperative mortality in a well-defined French population. Methods Data on 30- and 90-day postoperative mortality after resection for colorectal cancer were extr...

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Bibliographic Details
Published in:International journal of colorectal disease 2017-12, Vol.32 (12), p.1725-1731
Main Authors: Manfredi, Sylvain, Jooste, Valérie, Gay, Caroline, Faivre, Jean, Drouillard, Antoine, Bouvier, Anne-Marie
Format: Article
Language:English
Subjects:
Aged
Analysis
Cancer
Colon cancer
Colorectal cancer
Colorectal carcinoma
Comorbidity
Gastroenterology
Geriatrics
Health aspects
Health risk assessment
Hepatology
Internal Medicine
Laparoscopy
Life Sciences
Medicine
Medicine & Public Health
Mortality
Multivariate analysis
Obesity
Oncology, Experimental
Original Article
Population studies
Population-based studies
Proctology
Rectum
Santé publique et épidémiologie
Surgery
Trends
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Summary:Background Postoperative mortality after resection of colorectal cancer is an important issue. The aim of this study was to assess early postoperative mortality in a well-defined French population. Methods Data on 30- and 90-day postoperative mortality after resection for colorectal cancer were extracted from the digestive cancer registry of Burgundy. Time trends of postoperative mortality between 1989 and 2013 were described for the large population. Case-control studies (death within 30 or 90 days = cases, alive at 90 days = controls) focused on the association between postoperative mortality and surgical approach, obesity and other comorbidities over the last [2010–2013] period, using conditional logistic regressions. Results Among the 11,448 concerned patients, 30- and 90-day postoperative mortalities were 4.9 and 7.2%. Thirty-day operative mortality decreased from 7.2% (1989–1993) to 4.4% (2010–2013; p  
ISSN:0179-1958
1432-1262
DOI:10.1007/s00384-017-2918-1