Work of breathing in children with diffuse parenchymal lung disease

Highlights • We reported a large number of respiratory mechanics parameters in children with DPLD. • C l dyn and the PTPoes/min strongly correlated with absolute values of VC and FRCHe. • Work of breathing was increased mainly due to the elastic components. • Inspiratory and expiratory muscle streng...

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Bibliographic Details
Published in:Respiratory physiology & neurobiology 2015-01, Vol.206, p.45-52
Main Authors: Khirani, Sonia, Nathan, Nadia, Ramirez, Adriana, Aloui, Sabrina, Delacourt, Christophe, Clément, Annick, Fauroux, Brigitte
Format: Article
Language:English
Subjects:
Adolescent
Breathing pattern
Child
Child, Preschool
Diffuse parenchymal lung disease
Female
Human health and pathology
Humans
Interstitial lung disease
Life Sciences
Lung
Lung - pathology
Lung compliance
Lung Diseases, Interstitial
Lung Diseases, Interstitial - diagnosis
Lung Diseases, Interstitial - physiopathology
Male
Medical Education
Pediatrics
Pulmonary/Respiratory
Pulmonology and respiratory tract
Respiration
Respiratory Mechanics
Respiratory Mechanics - physiology
Respiratory Muscles
Respiratory Muscles - pathology
Statistics as Topic
Tidal Volume
Vital Capacity
Work of breathing
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Summary:Highlights • We reported a large number of respiratory mechanics parameters in children with DPLD. • C l dyn and the PTPoes/min strongly correlated with absolute values of VC and FRCHe. • Work of breathing was increased mainly due to the elastic components. • Inspiratory and expiratory muscle strengths were quite normal in these children. • Lung mechanics may constitute useful additional markers of functional abnormalities.
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2014.11.015