Validation of a simple clinical tool for screening of acute lacunar stroke—A substudy of the WAKE-UP trial

Introduction: Lacunar stroke represents around a quarter of all ischemic strokes; however, their identification with computed tomography in the hyperacute setting is challenging. We aimed to validate a clinical score to identify lacunar stroke in the acute setting, independently, with data from the...

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Bibliographic Details
Published in:International journal of stroke 2024-10, Vol.19 (8), p.935-941
Main Authors: Arba, Francesco, Rinaldi, Chiara, Jensen, Märit, Endres, Matthias, Fiebach, Jochen B, Lemmens, Robin, Muir, Keith W, Nighoghossian, Norbert, Pedraza, Salvador, Simonsen, Claus Z, Thijs, Vincent, Gerloff, Christian, Wardlaw, Joanna M, Thomalla, Götz
Format: Article
Language:English
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Life Sciences
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Summary:Introduction: Lacunar stroke represents around a quarter of all ischemic strokes; however, their identification with computed tomography in the hyperacute setting is challenging. We aimed to validate a clinical score to identify lacunar stroke in the acute setting, independently, with data from the WAKE-UP trial using magnetic resonance imaging. Methods: We analyzed data from the WAKE-UP trial and extracted Oxfordshire Community Stroke Project (OCSP) classification. Lacunar score was defined by National Institutes of Health Stroke Scale (NIHSS) 
ISSN:1747-4930
1747-4949
1747-4949
DOI:10.1177/17474930241253987