Evaluation of retinal toxicity and efficacy of the anticytomegalovirus compound 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine

• Published in: Antimicrobial Agents and Chemotherapy 1995-07, Vol.39 (7), p.1485-1488
• Main Authors: Besen, G, Chavez-de la Paz, E, Tatebayashi, M, Flores-Aguilar, M, Gangan, P A, Munguia, D, Wiley, C A, Jähne, G, Winkler, I, Helsberg, M
• Format: Article
• Language: English
• Subjects: Administration, Oral; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - pharmacokinetics; Antiviral Agents - pharmacology; Antiviral Agents - toxicity; Biological and medical sciences; Comparative Study; Drug Administration Routes; Eye - metabolism; Ganciclovir - pharmacology; Half-Life; Medical sciences; Pharmacology. Drug treatments; Prodrugs - pharmacokinetics; Purines; Purines - pharmacokinetics; Purines - pharmacology; Purines - toxicity; Rabbits; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S; Retina; Retina - drug effects; Vitreous Body
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.39.7.1485

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