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Metabolism of 2′,3′-Dideoxy-2′,3′-Didehydro-β-l(−)-5-Fluorocytidine and Its Activity in Combination with Clinically Approved Anti-Human Immunodeficiency Virus β-d(+) Nucleoside Analogs In Vitro
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| Published in: | Antimicrobial Agents and Chemotherapy 1998-07, Vol.42 (7), p.1799-1804 |
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| Main Authors: | , , , , , , |
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| cited_by | cdi_FETCH-LOGICAL-a4179-b862f675351a484966bee1449781441ee384ebed61305bf6f63db2203e0de3403 |
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| cites | cdi_FETCH-LOGICAL-a4179-b862f675351a484966bee1449781441ee384ebed61305bf6f63db2203e0de3403 |
| container_end_page | 1804 |
| container_issue | 7 |
| container_start_page | 1799 |
| container_title | Antimicrobial Agents and Chemotherapy |
| container_volume | 42 |
| creator | DUTSCHMAN, G. E BRIDGES, E. G LIU, S.-H GULLEN, E XIN GUO KUKHANOVA, M CHENG, Y.-C |
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| doi_str_mv | 10.1128/aac.42.7.1799 |
| format | article |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.42.7.1799</identifier><identifier>PMID: 9661024</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Anti-HIV Agents ; Anti-HIV Agents - metabolism ; Anti-HIV Agents - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Biological and medical sciences ; Cell Line ; Deamination ; Deoxycytidine Kinase - metabolism ; Didanosine - pharmacology ; DNA Polymerase gamma ; DNA, Mitochondrial ; DNA, Viral - biosynthesis ; DNA, Viral - drug effects ; DNA-Directed DNA Polymerase - metabolism ; Drug Interactions ; HIV Reverse Transcriptase - antagonists & inhibitors ; HIV Reverse Transcriptase - metabolism ; HIV-1 ; HIV-1 - drug effects ; HIV-1 - physiology ; Medical sciences ; Pharmacology. Drug treatments ; Phosphorylation ; Stavudine - pharmacology ; Virus Replication - drug effects ; Zalcitabine ; Zalcitabine - analogs & derivatives ; Zalcitabine - metabolism ; Zalcitabine - pharmacology ; Zidovudine - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 1998-07, Vol.42 (7), p.1799-1804</ispartof><rights>1998 INIST-CNRS</rights><rights>Copyright © 1998 American Society for Microbiology</rights><rights>Copyright © 1998, American Society for Microbiology 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a4179-b862f675351a484966bee1449781441ee384ebed61305bf6f63db2203e0de3403</citedby><cites>FETCH-LOGICAL-a4179-b862f675351a484966bee1449781441ee384ebed61305bf6f63db2203e0de3403</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.42.7.1799$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.42.7.1799$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,3175,3176,27905,27906,52732,52733,52734,53772,53774</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2347931$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9661024$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DUTSCHMAN, G. E</creatorcontrib><creatorcontrib>BRIDGES, E. G</creatorcontrib><creatorcontrib>LIU, S.-H</creatorcontrib><creatorcontrib>GULLEN, E</creatorcontrib><creatorcontrib>XIN GUO</creatorcontrib><creatorcontrib>KUKHANOVA, M</creatorcontrib><creatorcontrib>CHENG, Y.-C</creatorcontrib><title>Metabolism of 2′,3′-Dideoxy-2′,3′-Didehydro-β-l(−)-5-Fluorocytidine and Its Activity in Combination with Clinically Approved Anti-Human Immunodeficiency Virus β-d(+) Nucleoside Analogs In Vitro</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob. Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Anti-HIV Agents</subject><subject>Anti-HIV Agents - metabolism</subject><subject>Anti-HIV Agents - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. 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Drug treatments</topic><topic>Phosphorylation</topic><topic>Stavudine - pharmacology</topic><topic>Virus Replication - drug effects</topic><topic>Zalcitabine</topic><topic>Zalcitabine - analogs & derivatives</topic><topic>Zalcitabine - metabolism</topic><topic>Zalcitabine - pharmacology</topic><topic>Zidovudine - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DUTSCHMAN, G. E</creatorcontrib><creatorcontrib>BRIDGES, E. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>9661024</pmid><doi>10.1128/aac.42.7.1799</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 1998-07, Vol.42 (7), p.1799-1804 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_highwire_asm_aac_42_7_1799 |
| source | PubMed Central(OpenAccess); American Society for Microbiology Journals |
| subjects | Anti-HIV Agents Anti-HIV Agents - metabolism Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences Cell Line Deamination Deoxycytidine Kinase - metabolism Didanosine - pharmacology DNA Polymerase gamma DNA, Mitochondrial DNA, Viral - biosynthesis DNA, Viral - drug effects DNA-Directed DNA Polymerase - metabolism Drug Interactions HIV Reverse Transcriptase - antagonists & inhibitors HIV Reverse Transcriptase - metabolism HIV-1 HIV-1 - drug effects HIV-1 - physiology Medical sciences Pharmacology. Drug treatments Phosphorylation Stavudine - pharmacology Virus Replication - drug effects Zalcitabine Zalcitabine - analogs & derivatives Zalcitabine - metabolism Zalcitabine - pharmacology Zidovudine - pharmacology |
| title | Metabolism of 2′,3′-Dideoxy-2′,3′-Didehydro-β-l(−)-5-Fluorocytidine and Its Activity in Combination with Clinically Approved Anti-Human Immunodeficiency Virus β-d(+) Nucleoside Analogs In Vitro |
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