In Vitro Activity of Expanded-Spectrum Pyridazinyl Oxime Ethers Related to Pirodavir: Novel Capsid-Binding Inhibitors with Potent Antipicornavirus Activity

• Published in: Antimicrobial Agents and Chemotherapy 2004-05, Vol.48 (5), p.1766-1772
• Main Authors: BARNARD, D. L, HUBBARD, V. D, SMEE, D. F, SIDWELL, R. W, WATSON, K. G. W, TUCKER, S. P. T, REECE, P. A. R
• Format: Article
• Language: English
• Subjects: Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - pharmacology; Biological and medical sciences; Biological Availability; Capsid; Capsid - drug effects; Cell Line; Cytopathogenic Effect, Viral - drug effects; Enterovirus - drug effects; Enterovirus B, Human - drug effects; Haplorhini; Human rhinovirus; Humans; KB Cells; Medical sciences; Neutral Red; Oximes; Oximes - pharmacology; Pharmacology. Drug treatments; Picornaviridae; Picornaviridae - drug effects; Piperidines; Piperidines - pharmacology; Poliovirus; Pyridazines; Pyridazines - pharmacology; Rhinovirus - drug effects; Virus Replication - drug effects
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.48.5.1766-1772.2004

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