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Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes
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Published in: | Eukaryotic Cell 2013-01, Vol.12 (1), p.12-22 |
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creator | Chabrier-Roselló, Yeissa Gerik, Kimberly J Koselny, Kristy DiDone, Louis Lodge, Jennifer K Krysan, Damian J |
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</description><identifier>ISSN: 1535-9778</identifier><identifier>EISSN: 1535-9786</identifier><identifier>DOI: 10.1128/EC.00235-12</identifier><identifier>PMID: 23087368</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>3-Phosphoinositide-Dependent Protein Kinases ; Animals ; Antifungal Agents - pharmacology ; Cell Wall - enzymology ; Cryptococcus neoformans - enzymology ; Cryptococcus neoformans - growth & development ; Cryptococcus neoformans - pathogenicity ; Drug Resistance, Fungal ; Fluconazole - pharmacology ; Larva - microbiology ; Macrophages - microbiology ; Macrophages - physiology ; Mice ; Microbial Sensitivity Tests ; Microbial Viability ; Moths - microbiology ; Oxidative Stress ; Phagocytosis ; Protein-Serine-Threonine Kinases - genetics ; Protein-Serine-Threonine Kinases - metabolism ; Protein-Serine-Threonine Kinases - physiology ; Pyrazoles - pharmacology ; Reactive Oxygen Species - metabolism ; Stress, Physiological ; Sulfonamides - pharmacology ; Virulence</subject><ispartof>Eukaryotic Cell, 2013-01, Vol.12 (1), p.12-22</ispartof><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-3c82c8f2f50cd94bf992991258fc5e1d0a946d7971f7138ac4e4a34fd7b96913</citedby><cites>FETCH-LOGICAL-c475t-3c82c8f2f50cd94bf992991258fc5e1d0a946d7971f7138ac4e4a34fd7b96913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535849/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535849/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23087368$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chabrier-Roselló, Yeissa</creatorcontrib><creatorcontrib>Gerik, Kimberly J</creatorcontrib><creatorcontrib>Koselny, Kristy</creatorcontrib><creatorcontrib>DiDone, Louis</creatorcontrib><creatorcontrib>Lodge, Jennifer K</creatorcontrib><creatorcontrib>Krysan, Damian J</creatorcontrib><title>Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes</title><title>Eukaryotic Cell</title><addtitle>Eukaryot Cell</addtitle><description>Classifications
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</description><subject>3-Phosphoinositide-Dependent Protein Kinases</subject><subject>Animals</subject><subject>Antifungal Agents - pharmacology</subject><subject>Cell Wall - enzymology</subject><subject>Cryptococcus neoformans - enzymology</subject><subject>Cryptococcus neoformans - growth & development</subject><subject>Cryptococcus neoformans - pathogenicity</subject><subject>Drug Resistance, Fungal</subject><subject>Fluconazole - pharmacology</subject><subject>Larva - microbiology</subject><subject>Macrophages - microbiology</subject><subject>Macrophages - physiology</subject><subject>Mice</subject><subject>Microbial Sensitivity Tests</subject><subject>Microbial Viability</subject><subject>Moths - microbiology</subject><subject>Oxidative Stress</subject><subject>Phagocytosis</subject><subject>Protein-Serine-Threonine Kinases - genetics</subject><subject>Protein-Serine-Threonine Kinases - metabolism</subject><subject>Protein-Serine-Threonine Kinases - physiology</subject><subject>Pyrazoles - pharmacology</subject><subject>Reactive Oxygen Species - metabolism</subject><subject>Stress, Physiological</subject><subject>Sulfonamides - pharmacology</subject><subject>Virulence</subject><issn>1535-9778</issn><issn>1535-9786</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNpVkU9v1DAQxSMEoqVw4o4scQGhFP9J1vYFCaULVC1qRfduee3xxpC1g50s2i_BZ8ZlYQWnGWne_EbzXlU9J_icECreLrtzjClra0IfVKekLZ3kYvHw2HNxUj3J-SvGpJWcPa5OKMOCs4U4rX52aT9O0URj5owCRBfTVoeMbvuYxz76ELOfvIX6AkYIFsKErnzQGRBBr24vrshrdJOmPg5xgy4z-gLfZ5_AosJBd1OCnNEqDpB0MIB0sOhuTju_0wPyAX2ekw9QbulNNPsJ8tPqkdNDhmd_6lm1-rBcdZ_q65uPl93769o0vJ1qZgQ1wlHXYmNls3ZSUikJbYUzLRCLtWwWlktOHCdMaNNAo1njLF_LhSTsrHp3wI7zegvWlK-SHtSY_FanvYraq_8nwfdqE3eKFUdFIwvgzQFgUsw5gTvuEqzuU1HLTv1ORRFa1C_-PXfU_o2hCF4eBL3f9D-Kf0rnrYL5m4FhKARF7jG_AH7ul2E</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Chabrier-Roselló, Yeissa</creator><creator>Gerik, Kimberly J</creator><creator>Koselny, Kristy</creator><creator>DiDone, Louis</creator><creator>Lodge, Jennifer K</creator><creator>Krysan, Damian J</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20130101</creationdate><title>Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes</title><author>Chabrier-Roselló, Yeissa ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>23087368</pmid><doi>10.1128/EC.00235-12</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology Journals; PubMed Central |
subjects | 3-Phosphoinositide-Dependent Protein Kinases Animals Antifungal Agents - pharmacology Cell Wall - enzymology Cryptococcus neoformans - enzymology Cryptococcus neoformans - growth & development Cryptococcus neoformans - pathogenicity Drug Resistance, Fungal Fluconazole - pharmacology Larva - microbiology Macrophages - microbiology Macrophages - physiology Mice Microbial Sensitivity Tests Microbial Viability Moths - microbiology Oxidative Stress Phagocytosis Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Protein-Serine-Threonine Kinases - physiology Pyrazoles - pharmacology Reactive Oxygen Species - metabolism Stress, Physiological Sulfonamides - pharmacology Virulence |
title | Cryptococcus neoformans Phosphoinositide-Dependent Kinase 1 (PDK1) Ortholog Is Required for Stress Tolerance and Survival in Murine Phagocytes |
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