Attenuation of Phospholipid Signaling Provides a Novel Mechanism for the Action of Valproic Acid

• Published in: Eukaryotic Cell 2007-06, Vol.6 (6), p.899-906
• Main Authors: Xu, Xuehua, Müller-Taubenberger, Annette, Adley, Kathryn E, Pawolleck, Nadine, Lee, Vivian W Y, Wiedemann, Claudia, Sihra, Talvinder S, Maniak, Markus, Jin, Tian, Williams, Robin S B
• Format: Article
• Language: English
• Subjects: Amoeba; Animals; Anticonvulsants - metabolism; Anticonvulsants - pharmacology; Chemotaxis - drug effects; Chemotaxis - physiology; Dictyostelium - cytology; Dictyostelium - drug effects; Dictyostelium - physiology; Dictyostelium discoideum; Endocytosis - physiology; Enzyme Inhibitors - metabolism; Enzyme Inhibitors - pharmacology; Exocytosis - physiology; Humans; Inositol 1,4,5-Trisphosphate - metabolism; Phosphatidylinositol 3-Kinases - metabolism; Phospholipids - metabolism; Protozoan Proteins - genetics; Protozoan Proteins - metabolism; Rats; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - metabolism; Signal Transduction - physiology; Valproic Acid - metabolism; Valproic Acid - pharmacology
• ISSN: 1535-9778; 1535-9786
• DOI: 10.1128/EC.00104-06

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