Role of Francisella Lipid A Phosphate Modification in Virulence and Long-Term Protective Immune Responses

• Published in: Infection and Immunity 2012-03, Vol.80 (3), p.943-951
• Main Authors: KANISTANON, Duangjit, POWELL, Daniel A, HAJJAR, Adeline M, PELLETIER, Mark R, COHEN, Ilana E, SING WAY, Sing, SKERRETT, Shawn J, XIAOYUAN WANG, RAETZ, Christian R. H, ERNST, Robert K
• Format: Article
• Language: English
• Subjects: Animals; Bacteriology; Biological and medical sciences; Cytokines - genetics; Disease Models, Animal; Female; Francisella - immunology; Francisella - metabolism; Francisella - pathogenicity; Fundamental and applied biological sciences. Psychology; Gene Knockout Techniques; Gram-Negative Bacterial Infections - immunology; Gram-Negative Bacterial Infections - microbiology; Gram-Negative Bacterial Infections - mortality; Gram-Negative Bacterial Infections - pathology; Immunity, Innate; Lipid A - immunology; Lipid A - metabolism; Lipid A - toxicity; Mice; Mice, Inbred C57BL; Mice, Knockout; Microbiology; Miscellaneous; Molecular Pathogenesis; Phosphates - metabolism; Phosphoric Monoester Hydrolases - genetics; Phosphoric Monoester Hydrolases - metabolism; Receptors, Immunologic - genetics; Survival Analysis; Virulence
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.06109-11

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